Protein Alignment CG4797 and SLC2A3

DIOPT Version :9

• Sequence 1: NP_726368.2
• Gene: CG4797 / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 125/456 - (27%)
• Similarity: 200/456 - (43%)
• Gaps: 50/456 - (10%)

  Fly   100 TGSWIASV--HSLATPFGSLLSGPLADYLGRRRTLILSVIPLLLGWSTLA---IAKSIKVVIFAR 159
            |..|..||  .|:....||...|...:..|||.::::..:..:.|...:.   :|||::::|..|
Human    60 TSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGR 124

  Fly   160 FLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMV------YSLGSMMYWRSVAW 218
            .:.|...|:..|...:||.|.:...||........:....|||:.      :.|||...|..:..
Human   125 LVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLG 189

  Fly   219 CANVLPLLSMVSISFIPETPAWLLRN-GHEKRALQALSFLRGSEISAQ--KELNDMKQRLAKERV 280
            ...:..:|...::.|.||:|.:||.| ..|:.|.|.|..|.|::..:|  :|:.|...|:::|:.
Human   190 FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQ 254

  Fly   281 TTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAV 345
            .|..  .:|::...|   :|::|.||..|.|..||...|.:|:..:..:.|.: :...|.|...|
Human   255 VTVL--ELFRVSSYR---QPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ-EPIYATIGAGV 313

  Fly   346 VRVICCMVFCVVLIF-VRR--RRIMIVSGIGSGLFCLVLSVYQYARFDQPKMSYD--VFVGAGCL 405
            |..|    |.||.:| |.|  ||.:.:.|:|...||..|........|    :|:  .||..|.:
Human   314 VNTI----FTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKD----NYNGMSFVCIGAI 370

  Fly   406 LGYIIFNTALMVMPG----IMIGELFPARIRGRTAGGVFASMNVALFIFAKKFPALQAMLKMRGV 466
            |.::.|   ..:.||    .::.|||....|.........|...:.|:....||:....|... |
Human   371 LVFVAF---FEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAY-V 431

  Fly   467 FLVFGVSSFLLT--AFMCLFQPETKGRSLEHIEDYFNGDNWLWFRRDRGYK--TVNLQPLEPLKD 527
            |::|  :.||:|  ||.....|||:||:.|.|...|.|..   ...||..|  .:.:..:||.|:
Human   432 FIIF--TGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA---HGADRSGKDGVMEMNSIEPAKE 491

  Fly   528 T 528
            |
Human   492 T 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	109/408 (27%)
		Sugar_tr	89..497	CDD:278511	115/421 (27%)
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	112/415 (27%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910