DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and slc2a5

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001008187.1	Gene:	slc2a5 / 493549	XenbaseID:	XB-GENE-494009	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	527	Identity:	146/527 - (27%)
Similarity:	239/527 - (45%)	Gaps:	78/527 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 EQDDDAANRRGMMHQILATCAVLLLSA--GCGMPIGFSAILL----PQLMD-NNSTEI-----PI 96
            |:.::...|:|   ::.||..::.|.|  |.....|::...:    |.:.| .|||.|     |:
Frog     5 EKKEEPDERKG---RLTATLILVTLVATFGSSFQYGYNVASVNSPSPFMKDFYNSTNIERVGSPL 66

  Fly    97 D--VETGSW--IASVHSLATPFGSLLSGPLADYLGRRRTL----ILSVIPLLLGWSTLAIAKSIK 153
            :  ..|..|  ..|::.|...|||||.|||...|||:.||    |.|:||.:| ..|..:||:.:
Frog    67 EDAFLTLLWSLTVSLYPLGGFFGSLLVGPLVSKLGRKGTLLFNNIFSIIPAIL-MGTSVVAKTFE 130

  Fly   154 VVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMV------YSLGSMMY 212
            |:|.:|...|...|:......:|:.|.:..|||..:...|.:..:.||||.      |.||:...
Frog   131 VIIASRLFVGVCAGLSSNVVPMYVGEMSPKNLRGAIGIMPQLMITVGILMAQIFGIRYILGNTEG 195

  Fly   213 WRSVAWCANVLPLLSMVSISFIPETPAW-LLRNGHEKRALQALSFLRGSEISAQKELNDMKQRLA 276
            |..:.....:..:|.:..:.|.||:|.: ||..|:|.:|.:||..|||.| ....|:.:|.|...
Frog   196 WPILLALTGIPAVLELAFLPFFPESPRYTLLHKGNEDKAKKALQRLRGWE-DVDSEIKEMYQEDQ 259

  Fly   277 KERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQ-AA 340
            .|:...:.  ::..||..|.....|:.:||.::.|..||...|.:||..:....|.:.::.| ..
Frog   260 SEKAEGQL--SVRNLCTFRPLRWQLISIIVMNMGQQLSGINAVYYYADSIYKSAGVKEETIQYVT 322

  Fly   341 IATAVVRVICCMVFCVVLIFVRRRRIMIVSGIGS-GLFCLVLSVYQYARFDQPKMSYDVFVGAGC 404
            :||..|.|:..:. .|.::....||::::||.|: .:.|:||::   |...|..:|:..::...|
Frog   323 VATGSVNVLMTLA-AVFIVDSWGRRVLLLSGFGTCCISCVVLTI---ALVYQTTVSWMPYLSIAC 383

  Fly   405 LLGYIIFNT-ALMVMPGIMIGELF-----PARIRGRTAGGVFASMNVALFIFAKKFPALQAMLKM 463
            ::.|:|.:. ....:|.::..|:|     ||..  ..||.|....|   ||....|..|     |
Frog   384 IIIYVIGHAIGPSPIPYVITTEMFRQASRPAAF--MIAGSVHWLSN---FIIGLIFEFL-----M 438

  Fly   464 RGVFLVFGVSSFLLTAFMCL--------FQPETKGRSLEHIEDYFNGDNWLWFRRDRGYKTVN-- 518
            .|:    |...|:|.|.:||        ..|||||::...:..       |..:|:...:||:
Frog   439 NGL----GAYCFILFAAICLATFIFIYIVVPETKGKTFLEVSQ-------LMAKRNGLEETVDSK 492

  Fly   519 -LQPLEP 524
             .|.|.|
Frog   493 EFQDLNP 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	129/462 (28%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	128/443 (29%)
slc2a5	NP_001008187.1	MFS_GLUT_Class2	24..475	CDD:340990	134/472 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910