DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and CG14160

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_648380.2	Gene:	CG14160 / 39177	FlyBaseID:	FBgn0036066	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	103/504 - (20%)
Similarity:	188/504 - (37%)	Gaps:	120/504 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 MMHQILATCAVLLLSAGCGMPIGFSAILLP--QLMDNNSTEIPIDVETGSWIASVHSLATPF--G 115
            :..|.:|:.:::.:  ||||.:.:|....|  :.::|::|               |:|...:  |
  Fly    24 LQFQSMASASIVFV--GCGMRLAWSIFDTPAGKFLNNHNT---------------HNLMMSWFIG 71

  Fly   116 SLLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLC--------GFATGILGGP 172
            :.:...||....:|.|  .:|.....|: .:.||..:.||:...||.        |.|.|:....
  Fly    72 AAVGALLAALFVQRVT--KNVAYTSSGF-LMIIAGILNVVLPQHFLAACYSSVSVGAAYGLTQIQ 133

  Fly   173 GQVYIAETAEPNLRSLLIGAPYVAYSSGILMVYSLGSMMYWRSVAWCANVLPL------------ 225
            ..|..:|.|..::|.:|:....:....|:.|     .:.|.|  .| .|:.||
  Fly   134 ALVTGSEVAHKSIRGMLLSCEKIFLWLGVCM-----QVFYTR--VW-HNLRPLDTQGYEMHIDQL 190

  Fly   226 -----------LSMVSISFIPETPAWLLRNGHEKRALQALSFLRGSEISAQKELNDMKQRLAK-- 277
                       ..:::::...|:|..||....:....:.|..|.|...:....|.:..::|..
  Fly   191 HGMVLAGLGLGAVILALAHRLESPLLLLHQERDMAVGETLKALHGQSTTELVRLREDCRQLHSAR 255

  Fly   278 --ERVTTKTNENI--FQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFY--AVDMISEFGAEFDS 336
              ||...:..|::  :::..:|  |.|...|:   ||:.|:...:.:.|  |..::|..|.|.|.
  Fly   256 DWERFVEEPEESVADWRVWARR--ILPFFKVL---LLRCFATLAVSLSYNRAFVVVSWHGLECDM 315

  Fly   337 K---QAAIATAVVRVICCMV--------FCVVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARFD 390
            .   ..|.|..:..|:...|        .|.:.:|:....|::|.|:             :...:
  Fly   316 NCMYWLAFAGLIGSVLGAFVVDWQGRRKVCSLSLFLAGVVIVMVGGV-------------FDHLE 367

  Fly   391 QPKMS-YDV---FVGAGCLLGYIIFNTALMVMPGIMIGELFPARIRGRTAGGV-----FASMNVA 446
            ..|.| ||:   .:....||..:|....:.|...:...|.|....:.|...|:     ...:.:.
  Fly   368 SVKRSFYDINLLVIALLMLLFEVIVAGGVAVPALVYTAEAFSIAHKARCLAGILIVEQLLQLGLL 432

  Fly   447 LFIFAKKFPALQAMLKMRGVFLVFGVSSFL--LTAFMCLFQPETKGRSL 493
            |..|       :..:.:...|...||.||:  ||.||  |.|||:..:|
  Fly   433 LATF-------EHYITVSVFFFTIGVFSFIVGLTVFM--FMPETRQLTL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	96/484 (20%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	95/468 (20%)
CG14160	NP_648380.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900