DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and CG3285

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster

Alignment Length:	461	Identity:	113/461 - (24%)
Similarity:	204/461 - (44%)	Gaps:	37/461 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 RGMMHQILATCAVLLLSAGCGMPIGFSAILLPQLM-DNNSTEIPIDVETGSWIASVHSLATPFGS 116
            |.:.||.|.|..:.:.:...|:.:|:.:.::..|. |.:..:.|:.|...|||.|:..:.:..|:
  Fly    20 RRIRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVGIGSVMGN 84

  Fly   117 LLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQV----YI 177
            |::|.|.|.:||:..|....||....|..:...:|::.:...|.:    .||.||...|    :|
  Fly    85 LIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLM----AGITGGACYVVLPTFI 145

  Fly   178 AETAEPNLRSLLIGAPYVAYSSGILMVYSLGSMM-YWRSVAWCANVLPLLSMVSISFIPETPAWL 241
            :|.|:.|:|..|.....::.::|:|..|.:.:.: |:.|..:... ||:...:....|||||..|
  Fly   146 SEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSPPFIIG-LPVCYFICNFLIPETPHHL 209

  Fly   242 LRNGHEKRALQALSF---LRGSEISAQKELNDMKQRLAKERVTTKTNENIFQLCCQRVAIKPLVI 303
            :|.|..:.|.::..|   :|.::|.|:.|..:||..|.||: |.|.....::....|.|.|....
  Fly   210 VRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQ-TEKAKSFDYRDFITRPAFKAYAS 273

  Fly   304 VIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVRRRRIMI 368
            ..|..:...||.:|.|..|..|:.:......:.....|...|::::...|..::.....||.:|:
  Fly   274 AAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIGVLQIVGNYVTTLLCDKYGRRILML 338

  Fly   369 VSGIGSGLFCLVLSVYQY--ARFDQPKMSYDVFVGAGCLLGYIIFNTALMVMPGIMIGELFPARI 431
            .|.:|:.:.......:.:  ...|...:.:...|...|.:  .:.|..|:....:::.|||||:|
  Fly   339 TSTLGASVCLTAFGTFTFFAEAADLSSVDWLPLVILSCFV--FLCNIGLVGCLFVVLVELFPAKI 401

  Fly   432 RGRTAGGVFASMNVALFIFAKKFPALQAMLKMRGVFLVFGVS---------SFLLTAFMCLFQPE 487
            |..:.......::..:|:..|.||...|         |:|.|         :|....:.|.|..|
  Fly   402 RSVSVSTFVVILSSTVFLTLKIFPICMA---------VWGTSVTMWSCSGITFFSFLYFCFFLEE 457

  Fly   488 TKGRSL 493
            |.|:||
  Fly   458 TNGKSL 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	102/439 (23%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	104/424 (25%)
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	101/430 (23%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	92/394 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920