DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4797 and itr1

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_593858.2	Gene:	itr1 / 2543145	PomBaseID:	SPAC4F8.15	Length:	575	Species:	Schizosaccharomyces pombe

Alignment Length:	519	Identity:	109/519 - (21%)
Similarity:	204/519 - (39%)	Gaps:	64/519 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QVVPGSEFQCKKASYSSRKLSTIDEQDDDAANRRGMMHQILATCAVLLLSAGC-GMPIGFSAILL 83
            ||:|............||..|.|...:..|.|.......:.....||..:||. |:..|:...::
pombe    44 QVLPVDSVSRLSNGARSRSNSNISLSEPHALNDTVEDQPVSKWVWVLAFAAGIGGLLFGYDTGVI 108

  Fly    84 PQLMDNNSTEIPIDVETG---------SWIASVHSLATPFGSLLSGPLADYLGRRRTLILSVIPL 139
                  :...:.|....|         .:|.|..||....|.:::|.|||:.||:..:.::.|.:
pombe   109 ------SGALVVIGTSLGGHELTNGGKEFITSATSLGALLGGIIAGALADFFGRKPVIAIASIII 167

  Fly   140 LLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMV 204
            ::|......|..:..:|..||:.|:..||......:|::|.|...:|..|:....:..::|.::.
pombe   168 IVGSIVQVTAHHLWHMIVGRFVIGWGVGIASLIIPLYLSEIAPSKIRGRLVIIYVLLITAGQVIA 232

  Fly   205 YSLGSMMY-----WRSVAWCANVLPLLSMVSISFIPETPAWLLRNGHEKRALQALSFLRGS---- 260
            |.:.:...     ||.:...|.|.....:..:.::||:|..|::....:.|...|:.:..:
pombe   233 YGIDTAFEHVHNGWRWMVGLAMVPAAFQLFILIWLPESPRLLVKKERSQEAYNTLARIYPTAHPY 297

  Fly   261 EISA-----QKELND-----MKQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSG 315
            ||..     |:.:.|     ..|::.|.......|.:.|         :.|::......:|..||
pombe   298 EIKTKLYLIQEGVRDPFSGSRWQKIVKTFKELYFNPSNF---------RALILACGLQAMQQLSG 353

  Fly   316 TFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVRRRRIMI-VSG-IGSGLFC 378
            ...:::::..:....|....:....|..|...|...:.|.|:..|.||..::: |.| |.:.:.|
pombe   354 FNSLMYFSSTIFEVVGFNNPTATGLIIAATNFVFTIVAFGVIDFFGRRILLLLTVWGMIAALIVC 418

  Fly   379 LVLSVYQYARFDQ-------PKMSYDVFVGAGCLLGYIIFNTALMVMPGIMIGELFPARIRGRTA 436
            .|  .:.:...|:       ...::.:.|....::....:.:.|..:|. ...||||..:|| ..
pombe   419 AV--AFHFLPKDENGNYTSGQSNAWAIVVLISMIVYVASYASGLGNLPW-QQSELFPMSVRG-LG 479

  Fly   437 GGVFASMNVA--LFIFAKKFPALQAMLKMRGVFLVFGVSSFL--LTAFMCLFQPETKGRSLEHI 496
            .|:..::|.|  |.|.| .|..|.:.:...|.|.::|...||  |.|..|  .|:....::|.|
pombe   480 TGMSTAVNWAGNLGIGA-SFLTLMSEITPTGTFALYGGLCFLGWLGALFC--YPDLTDYTIEEI 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	97/461 (21%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	94/449 (21%)
itr1	NP_593858.2	Sugar_tr	90..544	CDD:278511	99/473 (21%)
itr1	NP_593858.2	MFS	92..529	CDD:119392	95/458 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810