Protein Alignment pippin and itr1

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_593858.2
• Gene: itr1 / 2543145
• PomBaseID: SPAC4F8.15
• Length: 575
• Species: Schizosaccharomyces pombe
• Alignment Length: 519
• Identity: 109/519 - (21%)
• Similarity: 204/519 - (39%)
• Gaps: 64/519 - (12%)

  Fly    20 QVVPGSEFQCKKASYSSRKLSTIDEQDDDAANRRGMMHQILATCAVLLLSAGC-GMPIGFSAILL 83
            ||:|............||..|.|...:..|.|.......:.....||..:||. |:..|:...::
pombe    44 QVLPVDSVSRLSNGARSRSNSNISLSEPHALNDTVEDQPVSKWVWVLAFAAGIGGLLFGYDTGVI 108

  Fly    84 PQLMDNNSTEIPIDVETG---------SWIASVHSLATPFGSLLSGPLADYLGRRRTLILSVIPL 139
                  :...:.|....|         .:|.|..||....|.:::|.|||:.||:..:.::.|.:
pombe   109 ------SGALVVIGTSLGGHELTNGGKEFITSATSLGALLGGIIAGALADFFGRKPVIAIASIII 167

  Fly   140 LLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMV 204
            ::|......|..:..:|..||:.|:..||......:|::|.|...:|..|:....:..::|.::.
pombe   168 IVGSIVQVTAHHLWHMIVGRFVIGWGVGIASLIIPLYLSEIAPSKIRGRLVIIYVLLITAGQVIA 232

  Fly   205 YSLGSMMY-----WRSVAWCANVLPLLSMVSISFIPETPAWLLRNGHEKRALQALSFLRGS---- 260
            |.:.:...     ||.:...|.|.....:..:.::||:|..|::....:.|...|:.:..:
pombe   233 YGIDTAFEHVHNGWRWMVGLAMVPAAFQLFILIWLPESPRLLVKKERSQEAYNTLARIYPTAHPY 297

  Fly   261 EISA-----QKELND-----MKQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSG 315
            ||..     |:.:.|     ..|::.|.......|.:.|         :.|::......:|..||
pombe   298 EIKTKLYLIQEGVRDPFSGSRWQKIVKTFKELYFNPSNF---------RALILACGLQAMQQLSG 353

  Fly   316 TFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVRRRRIMI-VSG-IGSGLFC 378
            ...:::::..:....|....:....|..|...|...:.|.|:..|.||..::: |.| |.:.:.|
pombe   354 FNSLMYFSSTIFEVVGFNNPTATGLIIAATNFVFTIVAFGVIDFFGRRILLLLTVWGMIAALIVC 418

  Fly   379 LVLSVYQYARFDQ-------PKMSYDVFVGAGCLLGYIIFNTALMVMPGIMIGELFPARIRGRTA 436
            .|  .:.:...|:       ...::.:.|....::....:.:.|..:|. ...||||..:|| ..
pombe   419 AV--AFHFLPKDENGNYTSGQSNAWAIVVLISMIVYVASYASGLGNLPW-QQSELFPMSVRG-LG 479

  Fly   437 GGVFASMNVA--LFIFAKKFPALQAMLKMRGVFLVFGVSSFL--LTAFMCLFQPETKGRSLEHI 496
            .|:..::|.|  |.|.| .|..|.:.:...|.|.::|...||  |.|..|  .|:....::|.|
pombe   480 TGMSTAVNWAGNLGIGA-SFLTLMSEITPTGTFALYGGLCFLGWLGALFC--YPDLTDYTIEEI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	98/477 (21%)
itr1	NP_593858.2	MFS_HMIT_like	93..531	CDD:340918	95/459 (21%)