Protein Alignment pippin and Slc2a1

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_620182.1
• Gene: Slc2a1 / 24778
• RGDID: 3704
• Length: 492
• Species: Rattus norvegicus
• Alignment Length: 440
• Identity: 126/440 - (28%)
• Similarity: 194/440 - (44%)
• Gaps: 61/440 - (13%)

  Fly    94 IPIDVETGSWIASV--HSLATPFGSLLSGPLADYLGRRRTLILS-----VIPLLLGWSTLAIAKS 151
            ||....|..|..||  .|:....||...|...:..|||.::::.     |..:|:|:|.|  .||
  Rat    56 IPSTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKL--GKS 118

  Fly   152 IKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILM--VYSLGSMM--- 211
            .:::|..||:.|...|:..|...:|:.|.:...||..|.....:....|||:  |:.|.|:|
  Rat   119 FEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNA 183

  Fly   212 -YWRSVAWCANVLPLLSMVSISFIPETPAWLLRN-GHEKRALQALSFLRGSEISAQKELNDMK-- 272
             .|..:.....:..||..:.:.|.||:|.:||.| ..|.||...|..|||: ....::|.:||
  Rat   184 DLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGT-ADVTRDLQEMKEE 247

  Fly   273 --QRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFD 335
              |.:.:::||      |.:|.......:|::|.:|..|.|..||...|.:|:..:..:.|.: .
  Rat   248 GRQMMREKKVT------ILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ-Q 305

  Fly   336 SKQAAIATAVVRVICCMVFCVVLIFV---RRRRIMIVSGIGSGLFCLVLSVYQYARFDQ-PKMSY 396
            ...|.|.:.:|..    .|.||.:||   ..||.:.:.|:.....|.||.....|..:| |.|||
  Rat   306 PVYATIGSGIVNT----AFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLEQLPWMSY 366

  Fly   397 DVFVGAGCLLGYIIFNTALMVMPG----IMIGELF-----PARIRGRTAGGVFASMNVALFIFAK 452
            ...|   .:.|::.|   ..|.||    .::.|||     ||.:  ..||  |::. .:.||...
  Rat   367 LSIV---AIFGFVAF---FEVGPGPIPWFIVAELFSQGPRPAAV--AVAG--FSNW-TSNFIVGM 420

  Fly   453 KFPALQAMLKMRG--VFLVFGVSSFLLTAFMCLFQPETKGRSLEHIEDYF 500
            .|   |.:.::.|  ||::|.|...|...|.....||||||:.:.|...|
  Rat   421 CF---QYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGF 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	124/433 (29%)
Slc2a1	NP_620182.1	MFS_GLUT_Class1	14..458	CDD:340989	122/429 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	468..492		126/440 (29%)