DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_006505885.1	Gene:	Slc2a3 / 20527	MGIID:	95757	Length:	495	Species:	Mus musculus

Alignment Length:	464	Identity:	129/464 - (27%)
Similarity:	209/464 - (45%)	Gaps:	65/464 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 TGSW--IASVHSLATPFGSLLSGPLADYLGRRRTLIL-----SVIPLLLGWSTLAIAKSIKVVIF 157
            |..|  ..::.|:....||...|...:..|||.:::|     .:...|:|::  .||:|::::|.
Mouse    62 TALWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFA--KIAESVEMLIL 124

  Fly   158 ARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMV------YSLGSMMYWRSV 216
            .|.|.|...|:..|...:||.|.:...||........:....|||:.      :.|||...|..:
Mouse   125 GRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGL 189

  Fly   217 AWCANVLPLLSMVSISFIPETPAWLLRNGHEK-RALQALSFLRGSEISAQ--KELNDMKQRLAKE 278
            .....:..:|...::.|.||:|.:||.|..|: :|.:.|..|.|:....|  :|:.|...|:::|
Mouse   190 LGLTIIPAILQSAALPFCPESPRFLLINKKEEDQATEILQRLWGTSDVVQEIQEMKDESVRMSQE 254

  Fly   279 RVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIAT 343
            :..|     :.:|......::||:|.||..|.|..||...|.:|:..:..:.|.: :...|.|..
Mouse   255 KQVT-----VLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ-EPIYATIGA 313

  Fly   344 AVVRVICCMVFCVVLIF-VRR--RRIMIVSGIGSGLFCLV-LSVYQYARFDQPKMSYDVFVGAGC 404
            .||..|    |.||.:| |.|  ||.:.:.|:|....|.| :::....:.|...||   ||   |
Mouse   314 GVVNTI----FTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDDYEAMS---FV---C 368

  Fly   405 LLGYIIFNTALMVMPG----IMIGELF-----PARIRGRTAGGVFASMNVALFIFAKKFPALQAM 460
            ::..:|:.....:.||    .::.|||     ||.|  ..||....:.|   |:....||:..|.
Mouse   369 IVAILIYVAFFEIGPGPIPWFIVAELFSQGPRPAAI--AVAGCCNWTSN---FLVGMLFPSAAAY 428

  Fly   461 LKMRGVFLVFGVSSFLLTAFMCLFQ----PETKGRSLEHIEDYFNGDNWLWFRRDRGYKTVNLQP 521
            |... ||::|  ::||:  |..:|.    ||||||:.|.|...|.|.    ....:|...|.|..
Mouse   429 LGAY-VFIIF--AAFLI--FFLIFTFFKVPETKGRTFEDIARAFEGQ----AHSGKGPAGVELNS 484

  Fly   522 LEPLKDTRG 530
            ::|:|:|.|
Mouse   485 MQPVKETPG 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	111/412 (27%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	119/429 (28%)
Slc2a3	XP_006505885.1	MFS_GLUT_Class1	14..458	CDD:340989	116/423 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910