Protein Alignment pippin and slcf-2

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_508586.2
• Gene: slcf-2 / 192084
• WormBaseID: WBGene00006865
• Length: 595
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 109/542 - (20%)
• Similarity: 194/542 - (35%)
• Gaps: 167/542 - (30%)

  Fly    51 NRRGMMH--QILATCAVLLLSAGCGMPIGFSAILLPQLMDNNSTEIPIDVETGSWIASVHSLATP 113
            |:....|  ::|.:..:..|:.||     |.|:|:..   .:..::|:.|
 Worm   106 NKENANHAWEMLVSSRIYGLAIGC-----FVAVLMSH---RHGRKLPVVV--------------- 147

  Fly   114 FGSLLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQVYIA 178
                  |.:.|.:|...||:::.:|           ..:.|....|.:.|...|::...|.|.::
 Worm   148 ------GTILDVIGVVLTLLITSVP-----------HGVTVATVGRLINGIGQGMVQTAGSVMLS 195

  Fly   179 ETAEPNLRSLLIGAPYVAYSSGIL--MVYSL----GSMMYWRSVAWCANVLPLL----SMVSISF 233
            |......|..::....:....|.|  |..||    |:...|:   | |...|||    ::|.|..
 Worm   196 ELPPLKTRGTVLATLTMWACMGELGGMTISLDEFFGTPELWQ---W-AMGFPLLLLLPALVVIWH 256

  Fly   234 IPETPAWLLRNGHEKRALQALSFLRGSEISAQKELND--MKQRLAKERVTTKTNEN--------- 287
            .||:|.:|.....|..|.:|:|:.: |....::.:.:  ::::...|.:..|.:||
 Worm   257 APESPRYLFIENREDEARKAMSYYQ-SPADCKQSIEEILLEKQFTMEMIKEKVDENGNTRKKEPA 320

  Fly   288 -IFQLCCQRVAIKPLVIVIVFSLLQMFSGTFI------VIFYAVDMISEFGAEFDSKQAA----- 340
             :....|:|:........:   |:.:|..||:      .|.|:..:...||......|.|
 Worm   321 GLLSSICERLKDGRFTRAL---LIALFVQTFVHLDDWLWISYSTQIFENFGLTSGKAQTASLIMS 382

  Fly   341 IATAVVRVI---CCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARFDQPKMS------- 395
            :..||:.:.   |...|       .||.::||..|.|.:|..:..|     |..|.:|
 Worm   383 LPQAVISIALLGCFDNF-------DRRTLLIVPTILSVIFGFLAIV-----FSSPGLSNVIPLFV 435

  Fly   396 -------YDVFVGAGCLLGYIIFNTALMVMPGIMIGELFPA--RIRGRTA--------GGVFASM 443
                   :|:.|.|      |...:|..::|     |||.|  ::.|...        |||..:
 Worm   436 IIPILATFDLSVAA------ISGESAYAIVP-----ELFLANDKVLGSAIVGIVQNGFGGVLTN- 488

  Fly   444 NVALFIFAKKFPALQAMLKMRGVFLVFGVSSFLLTAFMCL----------FQPETKGRSLEHIED 498
                        .|...|...|:       |.:|..|:.:          :.|||.|::.:.|..
 Worm   489 ------------CLLTALNTHGI-------SNVLIPFVAMNTVYVGVTYKWLPETAGKTPQEINR 534

  Fly   499 YFN----GDNWLWFRRDRGYKT 516
            :|:    |.|...:.:.:..||
 Worm   535 HFSPEFPGTNVFLYLKHKASKT 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	101/505 (20%)
slcf-2	NP_508586.2	MFS	110..532	CDD:475125	102/512 (20%)