Protein Alignment pippin and K08H10.6

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_505572.1
• Gene: K08H10.6 / 187181
• WormBaseID: WBGene00010698
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 488
• Identity: 109/488 - (22%)
• Similarity: 205/488 - (42%)
• Gaps: 89/488 - (18%)

  Fly    58 QILATCAVLLLSAGCGMPIGF--------SAILLPQLMDNNSTEIPIDVETGS----W--IASVH 108
            ::||| :|:...|| |...|:        |.||...::||.......::.:..    |  :|...
 Worm    19 RLLAT-SVVATFAG-GFHFGYLISAVNPLSEILQQFIVDNLQNRYSYELSSSQLSLIWSSLAGCL 81

  Fly   109 SLATPFGSLLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIK---VVIFARFLCG--FATGI 168
            .:....|:.:|..|...:|.|.:|:|:.|..|.......:|.|::   ::..:|.|.|  ||.||
 Worm    82 FIGAMIGAYISIFLLQSIGPRNSLLLAAILQLFSAPVFGLAYSLRLCELLPISRILSGIAFAIGI 146

  Fly   169 LGGPGQVYIAETAEPNLRSL-----------------LIGAPYVAYSSGILMVYSLGSMMYWRSV 216
             ...| |::.|.:....|.|                 .:|.|||           ||::..|:.:
 Worm   147 -SAQG-VFLTEISPAKFRGLTNSLSGLIGNCAFLLAATLGTPYV-----------LGTVTQWKYI 198

  Fly   217 AWCANVLPLLS-MVSISFIPETPAWLLRNGHEKRALQALSFLRGSEISAQKELNDMKQRLAKERV 280
            .:...:..:|. :|:|:...::|.:||..|.......|:....|.....:|.:.|:  |:....|
 Worm   199 FFIETIPCVLHILVNITTFHDSPTYLLSIGKISEGESAIKVYYGETCHIKKIMEDL--RIIDNGV 261

  Fly   281 TTKTNENIF--QLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIAT 343
            ..|:...|.  :.|.|.::   |.:.|.||:  .|||...:.|:...::...|  |..:.:|:|.
 Worm   262 KEKSLRQILKDKGCAQALS---LAVAINFSV--AFSGIVAISFFGTFLLQTIG--FSPEGSAVAN 319

  Fly   344 AV---VRVICCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLS--VYQYARFDQPKMSYDVFVGAG 403
            ::   ..::..::..:.:..:.||.::|.|.:...|..:.:.  |:.|   |..|   |.|:...
 Worm   320 SLCSFASIVSALLAAIAMDKIGRRPLLITSLLVLALINIFMMSLVFLY---DSTK---DSFLAWP 378

  Fly   404 CLLGYIIFNTALMVMPG---IMIG-ELFP----ARIRGRTAGGVFASMNVALFIFAKKFPALQAM 460
            .|..:::|.....:..|   :.|| ||.|    ::::..:....||...:...|:      ||.:
 Worm   379 FLALFVLFTFVFSIGIGPAAVFIGAELAPPGTISKMQSYSTSVQFAGSFICPIIY------LQLV 437

  Fly   461 LKMRG-VFLVFGVSSFLLTAFMCLFQPETKGRS 492
            ..:.| .|::|.|...:..|:..::.|||||:|
 Worm   438 ESIGGFAFMLFIVPLTITAAYFYMYLPETKGKS 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	109/487 (22%)
K08H10.6	NP_505572.1	MFS_GLUT_Class1_2_like	24..469	CDD:340915	104/479 (22%)