DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and F48E3.2

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_509266.1	Gene:	F48E3.2 / 185981	WormBaseID:	WBGene00018603	Length:	488	Species:	Caenorhabditis elegans

Alignment Length:	493	Identity:	99/493 - (20%)
Similarity:	206/493 - (41%)	Gaps:	93/493 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 MMHQILATCAVLLLSAGCGMP---IGFSAILL------PQLMDNNSTEIPIDVETGSWIA--SVH 108
            ::..:||..|:..:......|   ||...|.|      |..:.|:..|       .:|.|  :::
Worm    10 ILSAVLAITAIFQMGYTNAYPNTAIGSFRIFLNESANEPYTLSNSEFE-------WAWSAMLAIY 67

  Fly   109 SLATPFGSLLSGPLADYLGRRRTLILSV-----------------IPLLLGWSTLAIAKSIKVVI 156
            .:....||::|..:||.:||:.||.|..                 :||:.|:|.|.::.|..:.:
Worm    68 FIGFAAGSVISAGVADRIGRKWTLFLGTCGSLLSSLIALFAIILKMPLMFGFSRLVMSLSAAISM 132

  Fly   157 FARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMVYS--LGSMMYWRSVAWC 219
                     .|::     :...|::..::|.|      :::::.:..|.:  :|.:...:|:..
Worm   133 ---------NGLI-----LLFQESSPSHMRGL------ISFNAEMAFVITNLIGGLFGMQSILG- 176

  Fly   220 ANVLPLLSMVSIS---------FIPETPAWLLRNGHEK----RALQALSFLRGSEISAQKELNDM 271
            .|::.|:::..|.         |:.|:|.:|....|:.    ||||....::..| .....|||:
Worm   177 QNIVGLIAVSIIPSSVACFLTVFLKESPKYLFLKKHDATEAGRALQFYQNIKDEE-EKMNVLNDL 240

  Fly   272 KQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDS 336
            |  |.||.:..:.|.::|.:...:...:..::.:  :.:|:.:..:.|:||:.|.:.:.|..::.
Worm   241 K--LEKEEMGHQKNGSLFDIMANQPVRRGFLLGL--ATMQLTASVWPVVFYSTDFLMDAGFSYEL 301

  Fly   337 KQAAIATAVVRVICCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARFDQPKMSYDVFVG 401
            .: :::|.::.:........:.|..:..|..::.|..|.....:| |:..:..   ...|..::|
Worm   302 SE-SVSTGMLFLSSLSTIVGMFIVEKYSRKWLLIGTASVNIAAIL-VFSLSAI---LSHYWTWIG 361

  Fly   402 AGCLLGYIIFNTALMVMPG----IMIGELFPARIRGRTAGGVFA-SMNVALFIFAKKFPALQAML 461
            .||::..|:...:..|..|    .:..||.|...|..:...|.| :..|||.:....||    :.
Worm   362 YGCIICLILHGISYSVAMGPIAWFITSELVPINFRAASQSLVLALNHTVALVLAFLTFP----LY 422

  Fly   462 KMRG---VFLVFGVSSFLLTAFMCLFQPETKGRSLEHI 496
            |..|   :.:.|.:...|....:.|:.||||.:.:..|
Worm   423 KTIGPITLVIFFVIPGILCIIMLILYLPETKDKHINVI 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	91/470 (19%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	90/450 (20%)
F48E3.2	NP_509266.1	MFS_GLUT_Class1_2_like	12..455	CDD:340915	98/484 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52445
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930