Protein Alignment pippin and F48E3.2

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_509266.1
• Gene: F48E3.2 / 185981
• WormBaseID: WBGene00018603
• Length: 488
• Species: Caenorhabditis elegans
• Alignment Length: 493
• Identity: 99/493 - (20%)
• Similarity: 206/493 - (41%)
• Gaps: 93/493 - (18%)

  Fly    55 MMHQILATCAVLLLSAGCGMP---IGFSAILL------PQLMDNNSTEIPIDVETGSWIA--SVH 108
            ::..:||..|:..:......|   ||...|.|      |..:.|:..|       .:|.|  :::
 Worm    10 ILSAVLAITAIFQMGYTNAYPNTAIGSFRIFLNESANEPYTLSNSEFE-------WAWSAMLAIY 67

  Fly   109 SLATPFGSLLSGPLADYLGRRRTLILSV-----------------IPLLLGWSTLAIAKSIKVVI 156
            .:....||::|..:||.:||:.||.|..                 :||:.|:|.|.::.|..:.:
 Worm    68 FIGFAAGSVISAGVADRIGRKWTLFLGTCGSLLSSLIALFAIILKMPLMFGFSRLVMSLSAAISM 132

  Fly   157 FARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMVYS--LGSMMYWRSVAWC 219
                     .|::     :...|::..::|.|      :::::.:..|.:  :|.:...:|:..
 Worm   133 ---------NGLI-----LLFQESSPSHMRGL------ISFNAEMAFVITNLIGGLFGMQSILG- 176

  Fly   220 ANVLPLLSMVSIS---------FIPETPAWLLRNGHEK----RALQALSFLRGSEISAQKELNDM 271
            .|::.|:::..|.         |:.|:|.:|....|:.    ||||....::..| .....|||:
 Worm   177 QNIVGLIAVSIIPSSVACFLTVFLKESPKYLFLKKHDATEAGRALQFYQNIKDEE-EKMNVLNDL 240

  Fly   272 KQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDS 336
            |  |.||.:..:.|.::|.:...:...:..::.:  :.:|:.:..:.|:||:.|.:.:.|..::.
 Worm   241 K--LEKEEMGHQKNGSLFDIMANQPVRRGFLLGL--ATMQLTASVWPVVFYSTDFLMDAGFSYEL 301

  Fly   337 KQAAIATAVVRVICCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARFDQPKMSYDVFVG 401
            .: :::|.::.:........:.|..:..|..::.|..|.....:| |:..:..   ...|..::|
 Worm   302 SE-SVSTGMLFLSSLSTIVGMFIVEKYSRKWLLIGTASVNIAAIL-VFSLSAI---LSHYWTWIG 361

  Fly   402 AGCLLGYIIFNTALMVMPG----IMIGELFPARIRGRTAGGVFA-SMNVALFIFAKKFPALQAML 461
            .||::..|:...:..|..|    .:..||.|...|..:...|.| :..|||.:....||    :.
 Worm   362 YGCIICLILHGISYSVAMGPIAWFITSELVPINFRAASQSLVLALNHTVALVLAFLTFP----LY 422

  Fly   462 KMRG---VFLVFGVSSFLLTAFMCLFQPETKGRSLEHI 496
            |..|   :.:.|.:...|....:.|:.||||.:.:..|
 Worm   423 KTIGPITLVIFFVIPGILCIIMLILYLPETKDKHINVI 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	98/486 (20%)
F48E3.2	NP_509266.1	MFS_GLUT_Class1_2_like	12..455	CDD:340915	98/484 (20%)