Protein Alignment pippin and Y39E4B.5

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_499720.1
• Gene: Y39E4B.5 / 176735
• WormBaseID: WBGene00012716
• Length: 505
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 133/522 - (25%)
• Similarity: 204/522 - (39%)
• Gaps: 124/522 - (23%)

  Fly    68 LSAGCGMPIGF-----------------SAILLPQLMDNNSTEIPIDVET-GSWIASVHSLATPF 114
            |||....|.||                 :::..|.:.|:.:|.......| ..|.     :|..|
 Worm    15 LSAITNFPSGFTNSSVNTAVEKLHKFIATSLRQPGVPDDENTIALFQSATLNCWF-----VAQIF 74

  Fly   115 GSLLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLCGFA-------------- 165
            |::::..::|..||:...|:.|                ...|||.|:..|:
 Worm    75 GAIMTPMISDGYGRKFGYIVCV----------------TTTIFATFVQYFSICFYMPWGLILGRS 123

  Fly   166 -TGILGGPGQ----VYIAETAEPNLRSLLIGAPYVAYSSGILMVYSLGSMMYWRSV-AWCANVLP 224
             |.::...|.    :|:.||:...:|.:......:.|  |.:.|  ||.::..:|| ....:.|.
 Worm   124 LTALVSPLGDACLLLYVQETSPLEIRGMSSFLCEIGY--GTMCV--LGMVLGMKSVLGESLSRLL 184

  Fly   225 LLSMV----SISF---IPETPAWL--LRNGHEKRALQALSFLRG---------SEISAQKELNDM 271
            |||::    |:.|   |||||.:|  :||..|| ||::|.|.:|         ||..|:|    |
 Worm   185 LLSLIPLFCSLCFIVRIPETPKFLMIMRNDREK-ALKSLEFFQGESSDNAYIMSEYQAEK----M 244

  Fly   272 KQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVF-SLLQMFSGTFIVIFYAVDMISEFGAEFD 335
            ..:|:::................|:|:..|.:.:.| .:||  |.|:.::        |.|...|
 Worm   245 TDKLSQDSTFVDLLSKWHLRQAMRLALATLSLTLSFYPILQ--SSTYFLL--------ESGVSVD 299

  Fly   336 SKQAAIATAVVRVICCMVFCVVLIFVR--RRRIMIVSGIGSGLFCLVLSVYQY--ARFDQPKMSY 396
            ..|.....|.| |:.....|...|..|  ||:::|..||.|.:..:..|.:.:  |....| .|:
 Worm   300 MAQICSTMAQV-VLTLSSICGASIIDRFSRRKLLITFGILSNVLLVAFSFFSHLSATVVSP-YSW 362

  Fly   397 DVFVGAGCLLGYII-FNTALMVMPGIMIGELFPARIRGRTAGGVFASMN--VALFIFAKKFPALQ 458
            ..:.....||.|.| |...|..:...:..||...|.|.......||..|  :||..|| ..|..:
 Worm   363 PKYACLASLLAYCISFGMVLGPLSWFVAPELVSQRHRCTIFSACFAIHNLLIALTDFA-TIPLFR 426

  Fly   459 AMLKMRGVFLVFGVSSFLLTAFMCLFQPETKGRS-LEHIEDYFNGDNWLWFRRDRG-----YKTV 517
            ....|..||| |.|.||....::.||.|||.|:| |:.|.:..          |||     :..|
 Worm   427 IFGSMCFVFL-FVVPSFFCLCYIYLFMPETLGKSTLDIIHEMI----------DRGLHGSEHHLV 480

  Fly   518 NL 519
            ||
 Worm   481 NL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	126/491 (26%)
Y39E4B.5	NP_499720.1	MFS	13..458	CDD:475125	123/486 (25%)