DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and Slc2a13

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_598295.2	Gene:	Slc2a13 / 171147	RGDID:	621814	Length:	637	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	106/495 - (21%)
Similarity:	194/495 - (39%)	Gaps:	118/495 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 ATPFGSLLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQV 175
            |....:|..|.|...||||..::|:.....:|.:.||.|.:.:.::..|.:.|...||......|
  Rat   119 AAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPV 183

  Fly   176 YIAETAEPNLRSLLIGAPYVAYSSGILMVYSL-GSMMY-----WRSVAWCANVLPLLSMVSISFI 234
            ||||.:.||||..|:....:..:.|......: |:..|     ||.:...|.:..::..:...|:
  Rat   184 YIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFL 248

  Fly   235 PETPAWLLRNGHEKRALQALSFLRGSEISAQKELNDMKQRLAKERVTTKTNENIFQLCCQRVAIK 299
            ||:|.||::.|..::|.:.||.:||:: :..:|.:.::..:.:|.   |.......:.|:.::..
  Rat   249 PESPRWLIQKGQTQKARRILSQMRGNQ-TIDEEYDSIRNSIEEEE---KEASAAGPIICRMLSYP 309

  Fly   300 P----LVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIF 360
            |    |.:.....:.|..||...:::|:..::...|.|.|  :.||..|.:......:|.:|.::
  Rat   310 PTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD--RLAIWLASITAFTNFIFTLVGVW 372

  Fly   361 ----VRRRRIMIVSGIGSGLFCLVLSV----------------------------YQYAR---FD 390
                |.||::...|..|:.:...:|::                            |.|..   .|
  Rat   373 LVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLD 437

  Fly   391 QP-----KMSYDVFVGAGC------------------------------------------LLGY 408
            ..     |::....:.:.|                                          |:|.
  Rat   438 PDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGL 502

  Fly   409 II----FNTALMVMPGIMIGELFP--ARIRGRT-AGGVFASMNVAL---FIFAKKFPALQAMLKM 463
            ::    |...:..||..:..|::|  ||..|.. :.|:....||.:   |:...::      |..
  Rat   503 VLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEY------LTY 561

  Fly   464 RGVFLVF-GVSSF-LLTAFMCLFQPETKGRSLEHIEDYFN 501
            .|.|.:: |.::. ||..:.||  |||||:.||.||..|:
  Rat   562 YGAFFLYAGFAAVGLLFVYGCL--PETKGKKLEEIESLFD 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	95/476 (20%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	103/489 (21%)
Slc2a13	NP_598295.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..38
		MFS	75..580	CDD:119392	94/472 (20%)
		Sugar_tr	78..598	CDD:278511	105/492 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820