Protein Alignment CG4797 and SLC2A6

DIOPT Version :9

• Sequence 1: NP_726368.2
• Gene: CG4797 / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_060055.2
• Gene: SLC2A6 / 11182
• HGNCID: 11011
• Length: 507
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 116/467 - (24%)
• Similarity: 210/467 - (44%)
• Gaps: 34/467 - (7%)

  Fly    60 LATCAVLLLSAGCGMPIGFSAILLPQLMDNNSTEIPIDVETGSWIASVHSLATPFGSLLSGPLAD 124
            |||.|.:|.:...|..:.:::.::|.|..:...::.:.....||..||.:|....|.|.:..|.|
Human    40 LATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILND 104

  Fly   125 YLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLL 189
            .|||:.:::.|.:|...|::.:|.|..:.:::..|.|.|||.|:......||::|.|.|.:|..|
Human   105 LLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGAL 169

  Fly   190 IGAPYVAYSSGILMVYSLGSMMYWRSVAWCANVLPLLSMVSISFIPETPAWLLRNGHEKRALQAL 254
            ...|.:....|.|.:|:||.::.||.:|.......|:.::.:||:|.:|.:||..|.::.||:||
Human   170 GATPQLMAVFGSLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234

  Fly   255 SFLRGSEISAQKELNDMKQRLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIV 319
            ::|||:::....|...::..:.::.......|......|     :|:.:.::..|||..:|...:
Human   235 AWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVC-----RPITVALLMRLLQQLTGITPI 294

  Fly   320 IFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLSVY 384
            :.|...:..........|..|.....||::..::..:.:....|:.::.||  .:.:|...|::.
Human   295 LVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS--AAIMFAANLTLG 357

  Fly   385 QYARFDQPKMSYDVFVG----------------AGCLLGYIIFNTALMVMPGIMIG--------- 424
            .|..|....:|.:...|                ||.|....:..|.|.:| |..:|
Human   358 LYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIM-GYAVGWGPITWLLM 421

  Fly   425 -ELFPARIRGRTAGGVFASMNVALFIFAKKFPALQAMLKMRGVFLVFGVSSFLLTAFMCLFQPET 488
             |:.|.|.||..:|....:..:..|:..|.|..:.:...::..|..|.....:...|.....|||
Human   422 SEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPET 486

  Fly   489 KGRSLEHIEDYF 500
            ||||||.||.:|
Human   487 KGRSLEQIESFF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	101/445 (23%)
		Sugar_tr	89..497	CDD:278511	105/433 (24%)
SLC2A6	NP_060055.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS_GLUT6_Class3	39..493	CDD:340992	112/460 (24%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	286..292		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920