DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5543 and TAF5

DIOPT Version :9

Sequence 1:	NP_611832.1	Gene:	CG5543 / 37768	FlyBaseID:	FBgn0034908	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_197897.3	Gene:	TAF5 / 832586	AraportID:	AT5G25150	Length:	669	Species:	Arabidopsis thaliana

Alignment Length:	417	Identity:	86/417 - (20%)
Similarity:	163/417 - (39%)	Gaps:	90/417 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SNETEAEDAKE-STEASGNGGGFKKMDKEQ------MIRQIEDV-----------------AEDL 64
            |.:.:|:|:|: |||....|...||:.|::      .:.::|.:                 :.|:
plant   257 SKDGDADDSKKRSTEIGKQGSSLKKLKKDKAGNATAKVARLETITVSPAPRVKPELALPVMSTDV 321

  Fly    65 ESQHLKEVMGISGFGRKAAKVFDINEQIEKARVTRPGMD--------KKREESKPKEDDQKDEEE 121
            |...|:                |:..:::.:.|..|.:.        .....|....|
plant   322 EQSILE----------------DLRNRVQLSSVAMPSVSFYTFVNTHNGLNCSSISHD------- 363

  Fly   122 EDVIGPLPPAVTTDKEKATKESSKDEDSDDDDYSSDEDSDDEQSLAKRIPYTHEVQMQHGSRAVL 186
                |.|.....:|......:.:|...:......::.||.| ||:......::.:.:.| |..|.
plant   364 ----GSLVAGGFSDSSIKVWDMAKIGQAGSGALQAENDSSD-QSIGPNGRRSYTLLLGH-SGPVY 422

  Fly   187 ALAGDPSGARLVSGSIDYDMCFWDFAGMDSSMRSFRQLQPCENHPIRSLQYSVTGDMILVISGNA 251
            :....|.|..::|.|.|..:..|. ..:::::..::.    .|:|:...|:|..|......|.:.
plant   423 SATFSPPGDFVLSSSADTTIRLWS-TKLNANLVCYKG----HNYPVWDAQFSPFGHYFASCSHDR 482

  Fly   252 QAKVLDRDGFEKLECCKGDQYISDMSRTKGHVAQLTSGCWHPFNREQFLTAALDGTLRIWQGLKS 316
            .|::...|..:.|....|  ::||:...:          ||| |.....|.:.|.|:|:|. :::
plant   483 TARIWSMDRIQPLRIMAG--HLSDVDCVQ----------WHP-NCNYIATGSSDKTVRLWD-VQT 533

  Fly   317 KEQLQVIKTRAQGGLRTNAASCNFNRDATLIAAGCVDGSIQTWDTRKMFVNTTHCVRDAHQKGSE 381
            .|.:::..     |.|:...|...:.|...:|:|..||:|..||     ::|..|:.......|.
plant   534 GECVRIFI-----GHRSMVLSLAMSPDGRYMASGDEDGTIMMWD-----LSTARCITPLMGHNSC 588

  Fly   382 ITSIVFSYMGQQLATRSNDETMKLWDL 408
            :.|:.:|..|..||:.|.|.|:||||:
plant   589 VWSLSYSGEGSLLASGSADCTVKLWDV 615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5543	NP_611832.1	WD40	<172..519	CDD:225201	57/237 (24%)
		WD40	180..497	CDD:295369	57/229 (25%)
		WD40 repeat	185..227	CDD:293791	7/41 (17%)
		WD40 repeat	233..268	CDD:293791	7/34 (21%)
		WD40 repeat	273..329	CDD:293791	12/55 (22%)
		WD40 repeat	337..374	CDD:293791	11/36 (31%)
		WD40 repeat	382..419	CDD:293791	12/27 (44%)
		WD40 repeat	427..469	CDD:293791
		WD40 repeat	475..497	CDD:293791
TAF5	NP_197897.3	TFIID_NTD2	64..188	CDD:398277
		WD40 repeat	357..416	CDD:293791	11/70 (16%)
		WD40	414..663	CDD:238121	57/232 (25%)
		WD40 repeat	422..458	CDD:293791	6/36 (17%)
		WD40 repeat	463..499	CDD:293791	7/35 (20%)
		WD40 repeat	506..541	CDD:293791	10/46 (22%)
		WD40 repeat	547..583	CDD:293791	11/40 (28%)
		WD40 repeat	589..622	CDD:293791	12/27 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910