DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5543 and AT5G08390

DIOPT Version :9

Sequence 1:	NP_611832.1	Gene:	CG5543 / 37768	FlyBaseID:	FBgn0034908	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_568194.2	Gene:	AT5G08390 / 830737	AraportID:	AT5G08390	Length:	839	Species:	Arabidopsis thaliana

Alignment Length:	432	Identity:	90/432 - (20%)
Similarity:	149/432 - (34%)	Gaps:	158/432 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   281 GHVAQLTSGCWHPFNREQFLTA--ALDGTLRIWQGLKSKEQLQVIKTRAQGGLRTNAASCNFNRD 343
            ||.:.:.|   ..|:..:.|.|  |..||:::|    ..|:.:|::|..  |.|:|..|.||:..
plant    57 GHSSGIDS---VTFDASEGLVAAGAASGTIKLW----DLEEAKVVRTLT--GHRSNCVSVNFHPF 112

  Fly   344 ATLIAAGCVDGSIQTWDTRKMFVNTTHCVR--DAHQKGSEITSIVFSYMGQQLATRSNDETMKLW 406
            ....|:|.:|.:::.||.||     ..|:.  ..|.:|  :..:.|:..|:.:.:...|..:|:|
plant   113 GEFFASGSLDTNLKIWDIRK-----KGCIHTYKGHTRG--VNVLRFTPDGRWIVSGGEDNVVKVW 170

  Fly   407 DLRQFKQPLHTWTNLFSRYDTTDCCFSPDDRLLVTGESLPKGQAEANLYFYSTKSYEEV------ 465
            ||...|. ||.:.:...:..:.|  |.|.:.||.|      |.|:..:.|:..:::|.:
plant   171 DLTAGKL-LHEFKSHEGKIQSLD--FHPHEFLLAT------GSADKTVKFWDLETFELIGSGGTE 226

  Fly   466 ---QRIPVSNAHVVKTL-----------WHPKLNQLFVSCGNGT-----------------IKCY 499
               .|....|......|           |.|      :.|.:|.                 :.|.
plant   227 TTGVRCLTFNPDGKSVLCGLQESLKIFSWEP------IRCHDGVDVGWSNLSDMNVHEGKLLGCS 285

  Fly   500 YDEHRSIRGAKLCV---VKTHRKRQPMEMVGVSQIITPHALPLFRQEKSRTSRKRMEKARMDPVK 561
            |:::        ||   |....:.:||. .|.:|                 |....||
plant   286 YNQN--------CVGVWVVDLSRTEPMS-GGATQ-----------------SNSHPEK------- 317

  Fly   562 SQRPDLPITSGQGGRVASSGGTLSSYVIRNLGLSKRVDDDQDPREAILKYAK-----DAAENPYW 621
                    |||.|...|......|..::..|..|::||       .:||..|     ..::|
plant   318 --------TSGSGRDQAGLNDNSSKVILGKLPGSQKVD-------PLLKETKSLGKLSVSQN--- 364

  Fly   622 IAPAYKQTQPKAIFSEKLPAD-------------EPATKKPK 650
                          |:.||.|             :|..|:||
plant   365 --------------SDPLPKDTKSTGRSSVSQSSDPLVKEPK 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5543	NP_611832.1	WD40	<172..519	CDD:225201	61/281 (22%)
		WD40	180..497	CDD:295369	56/256 (22%)
		WD40 repeat	185..227	CDD:293791
		WD40 repeat	233..268	CDD:293791
		WD40 repeat	273..329	CDD:293791	13/49 (27%)
		WD40 repeat	337..374	CDD:293791	11/38 (29%)
		WD40 repeat	382..419	CDD:293791	10/36 (28%)
		WD40 repeat	427..469	CDD:293791	11/50 (22%)
		WD40 repeat	475..497	CDD:293791	5/49 (10%)
AT5G08390	NP_568194.2	WD40	9..261	CDD:238121	54/234 (23%)
		WD40 repeat	63..99	CDD:293791	11/44 (25%)
		WD40 repeat	104..140	CDD:293791	11/40 (28%)
		WD40 repeat	147..182	CDD:293791	10/35 (29%)
		WD40 repeat	188..222	CDD:293791	10/41 (24%)
		Katanin_con80	680..831	CDD:404758
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910