DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5543 and AT2G43770

DIOPT Version :9

Sequence 1:	NP_611832.1	Gene:	CG5543 / 37768	FlyBaseID:	FBgn0034908	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_181905.1	Gene:	AT2G43770 / 818980	AraportID:	AT2G43770	Length:	343	Species:	Arabidopsis thaliana

Alignment Length:	323	Identity:	74/323 - (22%)
Similarity:	131/323 - (40%)	Gaps:	56/323 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 AVLALAGDPSGARLVSGSIDYDMCFWDFAGMDSSMRSFRQLQPCENHPIRSLQYSVTGDMILVIS 248
            ||..:..:|:|..:.|||.|.::..|...|   ..::|..|:..:| .|..|.::..|..|:..|
plant    55 AVYTMKFNPAGTLIASGSHDREIFLWRVHG---DCKNFMVLKGHKN-AILDLHWTSDGSQIVSAS 115

  Fly   249 GNAQAKVLDRDGFEKLECCKGDQYISDMSRTKGHVAQLTSGCWHPFNR--EQFLTAALDGTLRIW 311
            .:...:..|.:        .|.| |..|:.   |.:.:.|.|  |..|  ...::.:.|||.::|
plant   116 PDKTVRAWDVE--------TGKQ-IKKMAE---HSSFVNSCC--PTRRGPPLIISGSDDGTAKLW 166

  Fly   312 QGLKSKEQLQVIKTRAQGGLRT-----NAASCNFNRDATLIAAGCVDGSIQTWDTRKMFVNTTHC 371
            .            .|.:|.::|     ...:.:|:..|..|..|.||..::.||.||.....|
plant   167 D------------MRQRGAIQTFPDKYQITAVSFSDAADKIFTGGVDNDVKVWDLRKGEATMT-- 217

  Fly   372 VRDAHQKGSEITSIVFSYMGQQLATRSNDETMKLWDLRQFKQPLHTWTNLFSRY------DTTDC 430
             .:.||  ..||.:..|..|..|.|...|..:.:||:|.: .|.:....:|..:      :...|
plant   218 -LEGHQ--DTITGMSLSPDGSYLLTNGMDNKLCVWDMRPY-APQNRCVKIFEGHQHNFEKNLLKC 278

  Fly   431 CFSPDDRLLVTGESLPKGQAEANLYFYSTKSYEEVQRIPVSNAHVVKTLWHPKLNQLFVSCGN 493
            .:|||      |..:..|.::..::.:.|.|...:.::|.....|.:.::|| ...:..||.:
plant   279 SWSPD------GTKVTAGSSDRMVHIWDTTSRRTIYKLPGHTGSVNECVFHP-TEPIIGSCSS 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5543	NP_611832.1	WD40	<172..519	CDD:225201	74/323 (23%)
		WD40	180..497	CDD:295369	74/323 (23%)
		WD40 repeat	185..227	CDD:293791	11/41 (27%)
		WD40 repeat	233..268	CDD:293791	5/34 (15%)
		WD40 repeat	273..329	CDD:293791	12/57 (21%)
		WD40 repeat	337..374	CDD:293791	11/36 (31%)
		WD40 repeat	382..419	CDD:293791	11/36 (31%)
		WD40 repeat	427..469	CDD:293791	8/41 (20%)
		WD40 repeat	475..497	CDD:293791	5/19 (26%)
AT2G43770	NP_181905.1	WD40	49..340	CDD:238121	74/323 (23%)
		WD40 repeat	57..94	CDD:293791	10/39 (26%)
		WD40 repeat	99..135	CDD:293791	9/44 (20%)
		WD40 repeat	142..177	CDD:293791	10/48 (21%)
		WD40 repeat	183..219	CDD:293791	11/38 (29%)
		WD40 repeat	227..265	CDD:293791	9/38 (24%)
		WD40 repeat	275..299	CDD:293791	6/29 (21%)
		WD40 repeat	317..340	CDD:293791	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910