DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5543 and daw1

DIOPT Version :9

Sequence 1:NP_611832.1 Gene:CG5543 / 37768 FlyBaseID:FBgn0034908 Length:655 Species:Drosophila melanogaster
Sequence 2:NP_001037817.1 Gene:daw1 / 556760 ZFINID:ZDB-GENE-050419-255 Length:418 Species:Danio rerio


Alignment Length:353 Identity:79/353 - (22%)
Similarity:128/353 - (36%) Gaps:83/353 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    87 DINEQIEKARVTRPGMDKKREES------KPKED-DQKDEEE-------EDVIGPLPPAVTTDKE 137
            |:.|.:.:.|...|.:.....|.      |.:|. .||||.:       :..|.||.........
Zfish    40 DVEELVLEIRAAEPLITSSCVEQVKLLICKLQEKVSQKDERKFYLFRALQAHILPLTNVAFNKSG 104

  Fly   138 KATKESSKDEDSDDDDYSSDEDSDDEQSLAKRIPYTHEVQMQHGSR-AVLALA-GDPSGARLVSG 200
            ......|.|......|.:|.|                |:....|.| .|.|:| .:|.|.::.:|
Zfish   105 SCFITGSYDRTCKIWDTASGE----------------ELHTLEGHRNVVYAIAFNNPYGDKVATG 153

  Fly   201 SID---------YDMCFWDFAGMDSSMRSFRQLQPCENHPIRSLQYSVTGDMILVISGNAQAKVL 256
            |.|         ...||:.|.|..:.              |..|.::....::...|.:..||:.
Zfish   154 SFDKTCKLWSAETGKCFYTFRGHTAE--------------IVCLAFNPQSTLVATGSMDTTAKLW 204

  Fly   257 DRDGFEKLECCKGDQYISDMSRTKGHVAQLTSGCWHPFNR--EQFLTAALDGTLRIWQGLKSKEQ 319
            |.:..|            ::|...||.|::.|.|   ||.  ::.:|.:.|.|..:|. :.|..:
Zfish   205 DVESGE------------EVSTLAGHFAEIISLC---FNTTGDRLVTGSFDHTAILWD-VPSGRK 253

  Fly   320 LQVIKTRAQGGLRTNAASCNFNRDATLIAAGCVDGSIQTWDTRKMFVNTTHCVRDAHQKGSEITS 384
            :.|:     .|.|...:...||.|.:|||...:|.|.:.||     .....|:........|:..
Zfish   254 VHVL-----SGHRGEISCVQFNWDCSLIATASLDKSCKVWD-----AEGGQCLATLLGHNDEVLD 308

  Fly   385 IVFSYMGQQLATRSNDETMKLWDLRQFK 412
            :.|:|.||.:||.|.|.|.:::....|:
Zfish   309 VCFNYTGQLIATASADGTSRVFSTDTFQ 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5543NP_611832.1 WD40 <172..519 CDD:225201 60/254 (24%)
WD40 180..497 CDD:295369 59/246 (24%)
WD40 repeat 185..227 CDD:293791 12/51 (24%)
WD40 repeat 233..268 CDD:293791 6/34 (18%)
WD40 repeat 273..329 CDD:293791 14/57 (25%)
WD40 repeat 337..374 CDD:293791 11/36 (31%)
WD40 repeat 382..419 CDD:293791 10/31 (32%)
WD40 repeat 427..469 CDD:293791
WD40 repeat 475..497 CDD:293791
daw1NP_001037817.1 CEP19 4..>81 CDD:291594 11/40 (28%)
WD40 84..372 CDD:238121 68/309 (22%)
WD40 88..405 CDD:225201 68/305 (22%)
WD 1 90..129 9/54 (17%)
WD40 repeat 95..132 CDD:293791 7/52 (13%)
WD 2 132..172 12/39 (31%)
WD40 repeat 137..175 CDD:293791 11/37 (30%)
WD 3 175..214 8/64 (13%)
WD40 repeat 181..217 CDD:293791 7/47 (15%)
WD 4 217..256 12/42 (29%)
WD40 repeat 222..258 CDD:293791 10/44 (23%)
WD 5 259..298 13/43 (30%)
WD40 repeat 265..300 CDD:293791 11/39 (28%)
WD 6 301..340 11/36 (31%)
WD40 repeat 306..342 CDD:293791 10/31 (32%)
WD 7 343..384
WD40 repeat 348..384 CDD:293791
WD40 376..>405 CDD:197651
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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