DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5543 and ercc8

DIOPT Version :9

Sequence 1:NP_611832.1 Gene:CG5543 / 37768 FlyBaseID:FBgn0034908 Length:655 Species:Drosophila melanogaster
Sequence 2:NP_001005984.1 Gene:ercc8 / 449811 ZFINID:ZDB-GENE-041010-60 Length:400 Species:Danio rerio


Alignment Length:354 Identity:64/354 - (18%)
Similarity:114/354 - (32%) Gaps:135/354 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   213 GMDSSMR-----SFRQLQPCE-NH----------PIRSLQYSVTGDMILVISGNAQAKV----LD 257
            |:|..:|     |.|::...| ||          .|.:|...|. |...::||.:...:    |:
Zfish    11 GLDDPVRLRRAESTRRVLSLELNHNRDVDRIHGNGINTLDIEVI-DGRYMLSGGSDGVIVIYDLE 74

  Fly   258 RDGFEKLECCKGDQYISDMSRTKGHVAQLT--SGCWHPFNREQFLTAALDGTLRIWQG------- 313
            .:..:....||.   |..:.|:..||.:.:  :..|:|.:...|::::.|.|:::|..       
Zfish    75 NNSKKPQYTCKA---ICTVGRSSRHVHKFSVETVQWYPHDTGMFVSSSFDKTMKVWDAETLKPAD 136

  Fly   314 ------------------------------------LKSKEQLQVIKTRAQGGLRTNAASCNFN- 341
                                                |||..::.:::     |.|....|..:: 
Zfish   137 EFQFDGNVYCHHMSPIARKHSLVAVGTKDPKVQLCDLKSGSRIHILQ-----GHRGEILSVRWSP 196

  Fly   342 RDATLIAAGCVDGSIQTWDTRK----MFVNTTH----------CVRDAHQKGSEITSIVFSYMGQ 392
            |...::|....|..::.||.|:    :|....|          .|..||  ...:..:.|:..|.
Zfish   197 RYEHILATASTDSRVRIWDVRRASGSLFTLDQHNGDKSKASSEAVNTAH--NGRVNGLCFTADGL 259

  Fly   393 QLATRSNDETMKLWDLRQFKQPLHTW--------------------------------------- 418
            .|.|...|:.|:||:....:..|..:                                       
Zfish   260 HLLTTGTDDRMRLWNSGTGENTLVNYGKVVNESRKGLKFTVSRGCSPEFVFVPCGSSVAVYGLHS 324

  Fly   419 ----TNLFSRYDTTDCC-FSPDDRLLVTG 442
                |.|...|:..||| |.||.:.|.:|
Zfish   325 GELITMLRGHYNNVDCCEFHPDYQELYSG 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5543NP_611832.1 WD40 <172..519 CDD:225201 64/354 (18%)
WD40 180..497 CDD:295369 64/354 (18%)
WD40 repeat 185..227 CDD:293791 5/18 (28%)
WD40 repeat 233..268 CDD:293791 6/38 (16%)
WD40 repeat 273..329 CDD:293791 13/100 (13%)
WD40 repeat 337..374 CDD:293791 10/51 (20%)
WD40 repeat 382..419 CDD:293791 9/79 (11%)
WD40 repeat 427..469 CDD:293791 8/17 (47%)
WD40 repeat 475..497 CDD:293791
ercc8NP_001005984.1 WD40 13..362 CDD:225201 63/352 (18%)
WD40 40..362 CDD:238121 56/325 (17%)
WD40 repeat 103..140 CDD:293791 6/36 (17%)
WD40 repeat 144..183 CDD:293791 3/38 (8%)
WD40 repeat 190..227 CDD:293791 8/36 (22%)
WD40 repeat 249..288 CDD:293791 9/38 (24%)
WD40 repeat 338..362 CDD:293791 8/16 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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