DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5543 and poc1b

DIOPT Version :9

Sequence 1:NP_611832.1 Gene:CG5543 / 37768 FlyBaseID:FBgn0034908 Length:655 Species:Drosophila melanogaster
Sequence 2:NP_956412.1 Gene:poc1b / 386932 ZFINID:ZDB-GENE-031118-54 Length:490 Species:Danio rerio


Alignment Length:514 Identity:112/514 - (21%)
Similarity:195/514 - (37%) Gaps:122/514 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   181 GSRAVLALAG-DPSGARLVSGSIDYDMCFWDFAGMDSSMRSFRQLQPCENHP--IRSLQYSVTGD 242
            |.:.|::.|. :|:..:|.:||.|..:..|:.|   ...|:||.:    .|.  |..:.::.:|.
Zfish    16 GHKDVISCADFNPNNKQLATGSCDKSLMIWNLA---PKARAFRFV----GHTDVITGVNFAPSGS 73

  Fly   243 MILVISGNAQAKVLDRDGFEKL--ECCKGDQYISDMSRTKGHVAQLTSGCWHPFNR--EQFLTAA 303
            ::...|         ||...:|  ...||:..:     .|.|.|.:.|   ..|:|  ::.:||:
Zfish    74 LVASSS---------RDQTVRLWTPSIKGESTV-----FKAHTASVRS---VNFSRDGQRLVTAS 121

  Fly   304 LDGTLRIWQGLKSKEQLQVIKTRAQGGLRTNAASC-NFNRDATLIAAGCVDGSIQTWDTRKMFVN 367
            .|.::::| |::.|:.|..:..      .||...| .|:.|..|||:...|.:::.|||     :
Zfish   122 DDKSVKVW-GVERKKFLYSLNR------HTNWVRCARFSPDGRLIASCGDDRTVRLWDT-----S 174

  Fly   368 TTHCVRDAHQKGSEITSIVFSYMGQQLATRSNDETMKLWDLRQFKQPLH-----TWTNLFSRYDT 427
            :..|.......|...|.:.|:..|..:|:...|.|:|:||:|..|...|     ...|.||    
Zfish   175 SHQCTNIFTDYGGSATFVDFNSSGTCIASSGADNTIKIWDIRTNKLIQHYKVHNAGVNCFS---- 235

  Fly   428 TDCCFSPDDRLLVTGES--------LPKGQAEANLYFYSTKSYEEVQRIPVSNAHVVKTLWHPKL 484
                |.|....|::|.|        |.:|:....|:               .:...|.|:...:.
Zfish   236 ----FHPSGNYLISGSSDSTIKILDLLEGRLIYTLH---------------GHKGPVLTVTFSRD 281

  Fly   485 NQLFVSCG-NGTIKCYYDEHRSIRGAKLCVVKTHRKRQPMEMVGVSQIITPHALPLFRQEKSRTS 548
            ..||.|.| :..:..:.....|:...:|  :..|.||       |:....||.:.::.:...| .
Zfish   282 GDLFASGGADSQVLMWKTNFDSLNYREL--LSRHSKR-------VTPDPPPHLMDIYPRSHHR-H 336

  Fly   549 RKRMEKARMDPV-KSQRPDLPITSGQGGRVASS-------GGTLSSYVIRNLGLS---------- 595
            ..:.....::|| .:|..|..:.  :.|||..|       .|..||......|:.          
Zfish   337 HPQNGTVEINPVADTQSTDPQVV--EVGRVVFSTTDARNYDGASSSRAQFTSGMDLGPLRTHTQA 399

  Fly   596 -KRVDDDQDPREAILKYAKDAAEN--PYWIAPAYKQ--------TQPKAIFSEKLPADE 643
             :..|::|:.|.|....|..|..:  |..:....:.        ||..|:..|:|...|
Zfish   400 REEEDENQEERFAGGMTASPAERSGIPSSLTSTLENIVQQLDILTQTVAVLEERLTLTE 458

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5543NP_611832.1 WD40 <172..519 CDD:225201 81/359 (23%)
WD40 180..497 CDD:295369 78/337 (23%)
WD40 repeat 185..227 CDD:293791 12/42 (29%)
WD40 repeat 233..268 CDD:293791 5/36 (14%)
WD40 repeat 273..329 CDD:293791 13/57 (23%)
WD40 repeat 337..374 CDD:293791 11/37 (30%)
WD40 repeat 382..419 CDD:293791 12/41 (29%)
WD40 repeat 427..469 CDD:293791 8/49 (16%)
WD40 repeat 475..497 CDD:293791 6/22 (27%)
poc1bNP_956412.1 WD40 10..298 CDD:238121 78/340 (23%)
WD40 14..>300 CDD:225201 78/342 (23%)
WD 1. /evidence=ECO:0000255 16..55 11/41 (27%)
WD40 repeat 22..58 CDD:293791 11/42 (26%)
WD 2. /evidence=ECO:0000255 58..97 9/47 (19%)
WD40 repeat 63..99 CDD:293791 8/49 (16%)
WD 3. /evidence=ECO:0000255 100..139 12/42 (29%)
WD40 repeat 106..141 CDD:293791 10/38 (26%)
WD 4. /evidence=ECO:0000255 142..181 13/49 (27%)
WD40 repeat 147..181 CDD:293791 11/38 (29%)
WD 5. /evidence=ECO:0000255 184..223 12/38 (32%)
WD40 repeat 189..225 CDD:293791 12/35 (34%)
WD 6. /evidence=ECO:0000255 226..265 10/46 (22%)
WD40 repeat 231..254 CDD:293791 8/30 (27%)
WD 7. /evidence=ECO:0000255 268..307 7/38 (18%)
WD40 repeat 273..314 CDD:293791 8/42 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 375..427 10/51 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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