DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5543 and AgaP_AGAP008233

DIOPT Version :9

Sequence 1:	NP_611832.1	Gene:	CG5543 / 37768	FlyBaseID:	FBgn0034908	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	XP_317237.3	Gene:	AgaP_AGAP008233 / 1277747	VectorBaseID:	AGAP008233	Length:	168	Species:	Anopheles gambiae

Alignment Length:	174	Identity:	77/174 - (44%)
Similarity:	104/174 - (59%)	Gaps:	19/174 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQRGKISFGKIKLNVNVPPAEPRSNETEAEDAKESTEASGNG-GGFKKMDKEQMIRQIEDVAEDL 64
            |.||||:||||.|..:.|.:   |....||....||||:.:| |.|.:.|..| ...:|.::.:|
Mosquito     1 MNRGKITFGKINLKSSTPTS---STNDSAEIPSTSTEATVSGFGSFGRKDNAQ-DEAVERISAEL 61

  Fly    65 ESQHLKEVMGISGFGRKAAKVFDINEQIEKARVTRP--GMDKKR-----EESKPKEDDQKDEEEE 122
            ::..|:|||||||||||.||.|||||.|:||:...|  .:|:|.     :|.|.|:||..|||||
Mosquito    62 DNSKLQEVMGISGFGRKQAKQFDINEMIQKAKQNAPKAAVDEKAIIDPDDERKGKDDDDDDEEEE 126

  Fly   123 --DVIGPLPPAV---TTDKEKATKESSKDEDSDDDDYSSDEDSD 161
              ::|||:|.|.   .||..:  |::.|:||..|||...||:.|
Mosquito   127 EDEMIGPVPTAAGGGATDSRR--KKADKEEDDSDDDDDDDEEDD 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG5543	NP_611832.1	WD40	<172..519	CDD:225201
		WD40	180..497	CDD:295369
		WD40 repeat	185..227	CDD:293791
		WD40 repeat	233..268	CDD:293791
		WD40 repeat	273..329	CDD:293791
		WD40 repeat	337..374	CDD:293791
		WD40 repeat	382..419	CDD:293791
		WD40 repeat	427..469	CDD:293791
		WD40 repeat	475..497	CDD:293791
AgaP_AGAP008233	XP_317237.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	262	1.000	Domainoid score	I4555
eggNOG	1	0.900	-	-		E1_KOG0772
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177718at33208
OrthoFinder	1	1.000	-	-		FOG0005020
OrthoInspector	1	1.000	-	-		otm51124
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4081
TreeFam	1	0.960	-	-
	8	7.780