| Sequence 1: | NP_611832.1 | Gene: | CG5543 / 37768 | FlyBaseID: | FBgn0034908 | Length: | 655 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_005877.2 | Gene: | KATNB1 / 10300 | HGNCID: | 6217 | Length: | 655 | Species: | Homo sapiens |
| Alignment Length: | 518 | Identity: | 113/518 - (21%) |
|---|---|---|---|
| Similarity: | 187/518 - (36%) | Gaps: | 159/518 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 180 HGSRAVLALAGDPSGARLVSG---------SIDYDMCFWDFAGMDSSMRSFRQLQPCENHPIRSL 235
Fly 236 QYSVTGDMILVISGNAQAKVLDRDGFEKLECCKGDQYISDMSRTKGHVAQLTSGCWHPFNREQFL 300
Fly 301 TAALDGTLRIWQGLKSKEQLQVIKTRAQGGLRTNAASCNFNRDATLIAAGCVDGSIQTWDTRKMF 365
Fly 366 VNTTHCVRDAHQKGSEITSIVFSYMGQQLATRSNDETMKLWDLRQFKQ----PLHTW-TNLFSRY 425
Fly 426 DTTDCCFSPDDRLLVTGESLPKGQAEANLYFYSTKSYEEVQRIPVSNAHVVKTLWHPKLNQLFVS 490
Fly 491 CGNGTIKCY-YDEHRSI--------RGAKLCVVKTHRKRQPMEMVGVS---QIITPHALPLFRQE 543
Fly 544 KSRTSRKRMEKARMDPVKSQRP---DLPITSGQGGRVASSGGTLSS---YVIRNLGLSKR---VD 599
Fly 600 DDQDPRE--AILKYAKDAAE--NPYWIAPAYKQTQPKAIFSEKLPA---DEPATKKPKTEADK 655 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG5543 | NP_611832.1 | WD40 | <172..519 | CDD:225201 | 71/361 (20%) |
| WD40 | 180..497 | CDD:295369 | 67/330 (20%) | ||
| WD40 repeat | 185..227 | CDD:293791 | 12/50 (24%) | ||
| WD40 repeat | 233..268 | CDD:293791 | 2/34 (6%) | ||
| WD40 repeat | 273..329 | CDD:293791 | 5/55 (9%) | ||
| WD40 repeat | 337..374 | CDD:293791 | 11/36 (31%) | ||
| WD40 repeat | 382..419 | CDD:293791 | 16/41 (39%) | ||
| WD40 repeat | 427..469 | CDD:293791 | 8/41 (20%) | ||
| WD40 repeat | 475..497 | CDD:293791 | 5/21 (24%) | ||
| KATNB1 | NP_005877.2 | Interaction with centrosomes | 1..300 | 73/382 (19%) | |
| Interaction with dynein. /evidence=ECO:0000250 | 1..284 | 71/366 (19%) | |||
| WD40 | 7..257 | CDD:238121 | 67/332 (20%) | ||
| WD40 repeat | 67..103 | CDD:293791 | 11/110 (10%) | ||
| WD40 repeat | 108..144 | CDD:293791 | 11/40 (28%) | ||
| WD40 repeat | 151..186 | CDD:293791 | 13/34 (38%) | ||
| WD40 repeat | 192..228 | CDD:293791 | 9/49 (18%) | ||
| WD40 repeat | 234..261 | CDD:293791 | 6/27 (22%) | ||
| Interaction with PAFAH1B1. /evidence=ECO:0000250 | 285..434 | 42/150 (28%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 311..422 | 37/124 (30%) | |||
| DNA_pol3_gamma3 | <386..>494 | CDD:331207 | 14/42 (33%) | ||
| Interaction with KATNA1 and NDEL1. /evidence=ECO:0000250 | 433..655 | ||||
| Katanin_con80 | 497..648 | CDD:316447 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||