DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ssrp and Hmgb2

DIOPT Version :9

Sequence 1:	NP_523830.2	Gene:	Ssrp / 37767	FlyBaseID:	FBgn0010278	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	NP_001350372.1	Gene:	Hmgb2 / 97165	MGIID:	96157	Length:	210	Species:	Mus musculus

Alignment Length:	206	Identity:	65/206 - (31%)
Similarity:	90/206 - (43%)	Gaps:	58/206 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   521 KKEKKSEKKEKKEKKHKEKE-RTKKPSK-----KKKDSGKPKRATTAFMLWLNDTRESIKRENPG 579
            |::.|.|...|.:|...::| :...|.|     ||||...|||..:||.|:.::.|..||.|:||
Mouse    55 KEKSKFEDLAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSENRPKIKIEHPG 119

  Fly   580 IKVTEIAKKGGEMWKE--LKDKSKWEDAAAKDKQRYHDEMRNYKPEAGGDSDNEKGGKSSKKRKT 642
            :.:.:.|||.||||.|  .|||..:|..|||.|::|..::..|:  |.|.|:      :.||...
Mouse   120 LSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYR--AKGKSE------AGKKGPG 176

  Fly   643 EPSPSKKANTSGSGFKSKEYISDDDSTSSDDEKDNEPAKKKSKPPSDGDAKKKKAKSESEPEESE 707
            .|:.|||.|                                  .|.|        :.|.|.||.|
Mouse   177 RPTGSKKKN----------------------------------EPED--------EEEEEEEEEE 199

  Fly   708 EDSNASDEDEE 718
            ||....:||||
Mouse   200 EDDEEEEEDEE 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssrp	NP_523830.2	POB3	20..499	CDD:227494
		SSrecog	75..284	CDD:281523
		PH2_SSRP1-like	332..427	CDD:270051
		HMG_box	557..620	CDD:278906	27/64 (42%)
Hmgb2	NP_001350372.1	HMG-box	7..78	CDD:320749	6/22 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	71..102		10/30 (33%)
		HMG_box	95..162	CDD:278906	29/66 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..210		22/97 (23%)
		Required for chemotactic activity. /evidence=ECO:0000250\|UniProtKB:P26583	165..180		5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910