Protein Alignment Ssrp and HMGB2

DIOPT Version :10

• Sequence 1: NP_523830.2
• Gene: Ssrp / 37767
• FlyBaseID: FBgn0010278
• Length: 723
• Species: Drosophila melanogaster
• Sequence 2: NP_002120.1
• Gene: HMGB2 / 3148
• HGNCID: 5000
• Length: 209
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 64/211 - (30%)
• Similarity: 90/211 - (42%)
• Gaps: 66/211 - (31%)

  Fly   521 KKEKKSEKKEKKEKKHKEKE-RTKKPSK-----KKKDSGKPKRATTAFMLWLNDTRESIKRENPG 579
            |::.|.|...|.:|...::| :...|.|     ||||...|||..:||.|:.::.|..||.|:||
Human    55 KEKSKFEDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPG 119

  Fly   580 IKVTEIAKKGGEMWKE--LKDKSKWEDAAAKDKQRYHDEMRNYKPEAGGDSDNEKGGKSSKKRKT 642
            :.:.:.|||.||||.|  .|||..:|..|||.|::|..::..|:  |.|.|:      :.||...
Human   120 LSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYR--AKGKSE------AGKKGPG 176

  Fly   643 EPSPSKKANTSGSGFKSKEYISDDDSTSSDDEKDNEPAKKKSKPPSDGDAKKKKAKSESEPEESE 707
            .|:.|||.|                                                  |||:.|
Human   177 RPTGSKKKN--------------------------------------------------EPEDEE 191

  Fly   708 EDSNASDEDEEDEASD 723
            |:....|||||:|..|
Human   192 EEEEEEDEDEEEEDED 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssrp	NP_523830.2	POB3	20..499	CDD:227494
		HMG-box_SSRP1-like	557..621	CDD:438810	27/65 (42%)
HMGB2	NP_002120.1	HMG-box_HMGB_rpt1	8..76	CDD:438794	6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	52..150		37/94 (39%)
		HMG-box_HMGB_rpt2	93..163	CDD:438795	29/69 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..209		23/104 (22%)
		Required for chemotactic activity. /evidence=ECO:0000269|PubMed:19811285	165..180		5/20 (25%)