DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ssrp and Hmgb3

DIOPT Version :9

Sequence 1:	NP_523830.2	Gene:	Ssrp / 37767	FlyBaseID:	FBgn0010278	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	NP_001280552.1	Gene:	Hmgb3 / 15354	MGIID:	1098219	Length:	200	Species:	Mus musculus

Alignment Length:	206	Identity:	60/206 - (29%)
Similarity:	86/206 - (41%)	Gaps:	66/206 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   521 KKEKKSEKKEKKEKKHKEKER----TKKPSKKKKDSGKPKRATTAFMLWLNDTRESIKRENPGIK 581
            |::.|.::..|.:|...::|.    ..|..|||||...|||..:.|.|:.::.|..||..||||.
Mouse    55 KEKSKFDEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGIS 119

  Fly   582 VTEIAKKGGEMWKELKDKSK--WEDAAAKDKQRYHDEMRNYKPEAGGDSDNEKGGKSSKKRKTEP 644
            :.::|||.||||..|.|..|  :...|||.|::|..::.:||.:  |..|..||
Mouse   120 IGDVAKKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDVADYKSK--GKFDGAKG----------- 171

  Fly   645 SPSKKANTSGSGFKSKEYISDDDSTSSDDEKDNEPAKKKSKPPSDGDAKKKKAKSESEPEESEED 709
                                              |||          ..:||.:.|.|.||.||:
Mouse   172 ----------------------------------PAK----------VARKKVEEEEEEEEEEEE 192

  Fly   710 SNASDEDEEDE 720
               .:|:||||
Mouse   193 ---EEEEEEDE 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssrp	NP_523830.2	POB3	20..499	CDD:227494
		SSrecog	75..284	CDD:281523
		PH2_SSRP1-like	332..427	CDD:270051
		HMG_box	557..620	CDD:278906	25/64 (39%)
Hmgb3	NP_001280552.1	HMG_box_2	13..78	CDD:370242	5/22 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	71..97		10/25 (40%)
		HMG_box	93..160	CDD:366139	27/66 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..200		19/98 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910