DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ssrp and HMG20A

DIOPT Version :9

Sequence 1:	NP_523830.2	Gene:	Ssrp / 37767	FlyBaseID:	FBgn0010278	Length:	723	Species:	Drosophila melanogaster
Sequence 2:	NP_001291433.1	Gene:	HMG20A / 10363	HGNCID:	5001	Length:	347	Species:	Homo sapiens

Alignment Length:	230	Identity:	59/230 - (25%)
Similarity:	103/230 - (44%)	Gaps:	45/230 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   469 DGDSDEESTDEDFKPNENESDVAEEYDSNVESDSDDD---SDASGGGGDSDGAKKKKEKKSEKKE 530
            |.|..:||.|. .....|..:|  .|.|...|.:::.   .|.|.|       :..:.:.|...|
Human    16 DEDGSKESNDL-ATTGLNHPEV--PYSSGATSSTNNPEFVEDLSQG-------QLLQSESSNAAE 70

  Fly   531 KKEKKHKEKERTK-----KPSKKKK---DSGKPKRATTAFMLWLNDTRESIKRENPGIKVTEIAK 587
            ..|::|::::|:|     |..|:||   ||..||...|.::.::|:.||.::.:.|.:...||.:
Human    71 GNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITR 135

  Fly   588 KGGEMWKEL--KDKSKWEDAAAKDKQRYHDEMRNY-KPEAGGDSDNEKGGKSSKKRKTEPSPSKK 649
            ..|..|.:|  ::|.::.|.|.:||:||..|:..| |.||          .....|||:.....|
Human   136 MLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEA----------YKVFSRKTQDRQKGK 190

  Fly   650 ANTSGSGFKSKEYISDDDSTSSDDEKDNEPAKKKS 684
            ::...:..::          :.|.||:.| .|::|
Human   191 SHRQDAARQA----------THDHEKETE-VKERS 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ssrp	NP_523830.2	POB3	20..499	CDD:227494	9/29 (31%)
		SSrecog	75..284	CDD:281523
		PH2_SSRP1-like	332..427	CDD:270051
		HMG_box	557..620	CDD:278906	18/64 (28%)
HMG20A	NP_001291433.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..113		28/106 (26%)
		DUF5401	<59..313	CDD:375164	46/177 (26%)
		HMGB-UBF_HMG-box	103..168	CDD:238686	20/64 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..211		8/42 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910