Protein Alignment CG5539 and REEP4

DIOPT Version :10

• Sequence 1: NP_611831.2
• Gene: CG5539 / 37766
• FlyBaseID: FBgn0034907
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_079508.2
• Gene: REEP4 / 80346
• HGNCID: 26176
• Length: 257
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 62/283 - (21%)
• Similarity: 124/283 - (43%)
• Gaps: 62/283 - (21%)

  Fly     6 LVSQFLFFVYGTMGPAWQTYKTLNSGD-EEFLAWAKYWIVYAFLVTFEVLADVFLSWLPLYMPTK 69
            ::.:.:..|:|.:.||:.:||.:.:.: .|::.|..||||:|..:..|::.|:|:||.|.|...|
Human     5 MICRLVVLVFGMLCPAYASYKAVKTKNIREYVRWMMYWIVFALFMAAEIVTDIFISWFPFYYEIK 69

  Fly    70 LLLVVWIVLSAPAANVWIFDAILRPVLAKRQEEIDHFLHRGKEK------------LLIDALASM 122
            :..|:|::.........::...:.|.|::.::|||.::.:.||:            |.|.|.|::
Human    70 MAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDAYIVQAKERSYETVLSFGKRGLNIAASAAV 134

  Fly   123 TQLVAQTQISVLPFVSSFWSRSSTAPLRT-SD----------LLQDST-------GEGIGGRTSE 169
             |...::|.::...:.||    |...||: ||          .|:|..       |...||....
Human   135 -QAATKSQGALAGRLRSF----SMQDLRSISDAPAPAYHDPLYLEDQVSHRRPPIGYRAGGLQDS 194

  Fly   170 DTDSANVSVQNLSSGSSPVGSLEHLRDDSEELLVGVSKATTHLQAEQFQSDVSSESPRIINRRPQ 234
            ||:                   :....|:|    .|.:|....:.:..   :.|:|.|::.|:|.
Human   195 DTE-------------------DECWSDTE----AVPRAPARPREKPL---IRSQSLRVVKRKPP 233

  Fly   235 RKFKNAIAIASATKLEDLHDDVE 257
            .:...:.::...|:.:.:..||:
Human   234 VREGTSRSLKVRTRKKTVPSDVD 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5539	NP_611831.2	TB2_DP1_HVA22	20..94	CDD:460820	21/74 (28%)
REEP4	NP_079508.2	TB2_DP1_HVA22	19..94	CDD:460820	21/74 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..257		17/100 (17%)