Protein Alignment CG5539 and REEP2

DIOPT Version :10

• Sequence 1: NP_611831.2
• Gene: CG5539 / 37766
• FlyBaseID: FBgn0034907
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_001258732.1
• Gene: REEP2 / 51308
• HGNCID: 17975
• Length: 254
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 67/277 - (24%)
• Similarity: 125/277 - (45%)
• Gaps: 45/277 - (16%)

  Fly     6 LVSQFLFFVYGTMGPAWQTYKTLNSGD-EEFLAWAKYWIVYAFLVTFEVLADVFLSWLPLYMPTK 69
            ::|:.:..::||:.||:.:||.:.:.: :|::.|..||||:||..|.|.|.|:.|||.|.|...|
Human     5 IISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLSWFPFYFELK 69

  Fly    70 LLLVVWIVLSAPAANVWIFDAILRPVLAKRQEEIDHFLHR------------GKEKLLIDALASM 122
            :..|:|::......:..::...:.|.|:.:::|||.::.:            ||..|.:.|.|::
Human    70 IAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMRVGKRGLNLAANAAV 134

  Fly   123 TQLVAQTQISVLPFVSSFWSRSSTAPLRTSDLLQDSTGEGIGGRTSEDTDSANVSVQNLSSGSSP 187
            | ..|:.|..:...:.|| |......:|..|.|.....:   ||......|...::::|  |..|
Human   135 T-AAAKGQGVLSEKLRSF-SMQDLTLIRDEDALPLQRPD---GRLRPSPGSLLDTIEDL--GDDP 192

  Fly   188 VGSLEHLRDDSEELLVGVSKATTHLQAEQFQSDVSSESPRIINRRPQRKFKNAIAIASATKLEDL 252
            ..||....:.::.            :.|..:.|:..::|:  ..:|.:|...|..:||.|
Human   193 ALSLRSSTNPADS------------RTEASEDDMGDKAPK--RAKPIKKAPKAEPLASKT----- 238

  Fly   253 HDDVEDLLAKTAMETSG 269
                  |..:...:|||
Human   239 ------LKTRPKKKTSG 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5539	NP_611831.2	TB2_DP1_HVA22	20..94	CDD:460820	24/74 (32%)
REEP2	NP_001258732.1	TB2_DP1_HVA22	19..94	CDD:460820	24/74 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..254		21/113 (19%)