Protein Alignment CG5539 and REEP3

DIOPT Version :10

• Sequence 1: NP_611831.2
• Gene: CG5539 / 37766
• FlyBaseID: FBgn0034907
• Length: 296
• Species: Drosophila melanogaster
• Sequence 2: NP_001001330.1
• Gene: REEP3 / 221035
• HGNCID: 23711
• Length: 255
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 62/261 - (23%)
• Similarity: 114/261 - (43%)
• Gaps: 39/261 - (14%)

  Fly     6 LVSQFLFFVYGTMGPAWQTYKTLNSGD-EEFLAWAKYWIVYAFLVTFEVLADVFLSWLPLYMPTK 69
            ::|:.:..|:|.:.||:.:||.:.:.: :|::.|..||||:|.....|.:||..::|.|||...|
Human     5 MISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVIETVADQTVAWFPLYYELK 69

  Fly    70 LLLVVWIVLSAPAANVWIFDAILRPVLAKRQEEIDHFLHRGKEK------------LLIDALASM 122
            :..|:|::.........|:...|.|:|:.::.|||.::.:.||:            |.:.|.|::
Human    70 IAFVIWLLSPYTKGASLIYRKFLHPLLSSKEREIDDYIVQAKERGYETMVNFGRQGLNLAATAAV 134

  Fly   123 TQLVAQTQISVLPFVSSFWSRSSTAPLRTSDLLQDSTGEGIGGRTSEDTDSANVSVQNLSSGSS- 186
            |..| ::|.::...:.||         ...||......|.:|.|..:....|....:...|.|:
Human   135 TAAV-KSQGAITERLRSF---------SMHDLTTIQGDEPVGQRPYQPLPEAKKKSKPAPSESAG 189

  Fly   187 ---PVGSLEHLRDDSEELLVGVSKATTH--LQAEQFQSDVSSESPR----------IINRRPQRK 236
               |:...:...|:..|.....::..||  |:..|....|.:...|          .:.:|||..
Human   190 YGIPLKDGDEKTDEEAEGPYSDNEMLTHKGLRRSQSMKSVKTTKGRKEVRYGSLKYKVKKRPQVY 254

  Fly   237 F 237
            |
Human   255 F 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5539	NP_611831.2	TB2_DP1_HVA22	20..94	CDD:460820	23/74 (31%)
REEP3	NP_001001330.1	TB2_DP1_HVA22	19..95	CDD:460820	23/75 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..242		15/83 (18%)