DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15800 and Skp1

DIOPT Version :9

Sequence 1:	NP_611828.1	Gene:	CG15800 / 37763	FlyBaseID:	FBgn0034904	Length:	157	Species:	Drosophila melanogaster
Sequence 2:	NP_035673.3	Gene:	Skp1 / 21402	MGIID:	103575	Length:	163	Species:	Mus musculus

Alignment Length:	168	Identity:	42/168 - (25%)
Similarity:	82/168 - (48%)	Gaps:	27/168 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VRFETRDGRTISVNLALLEKSLVIREMCR-VGQVPEDEDFVLPLHGIHSNVLLKILLWAEYHEKH 65
            ::.::.||....|::.:.::|:.|:.|.. :|...|.:|..:||..:::.:|.|::.|..:|:
Mouse     4 IKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHK-- 66

  Fly    66 EEPAWVDSKDPLPAEEIELQ------ISDWDKEFLRVEIDSICKIMEGCNYLDIPWLYKL-CAQK 123
                    .||.|.|:.|.:      |..||:|||:|:..::.:::...|||||..|..: |...
Mouse    67 --------DDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTV 123

  Fly   124 LVFLSSREPETQFSGYVEKIPRFQDHFIE----QIQKE 157
            ...:..:.||.     :.|....::.|.|    |::||
Mouse   124 ANMIKGKTPEE-----IRKTFNIKNDFTEEEEAQVRKE 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15800	NP_611828.1	BTB	1..113	CDD:295341	30/117 (26%)
Skp1	NP_035673.3	BTB_POZ_SKP1	3..127	CDD:349631	34/132 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..83		6/29 (21%)
		Interaction with the F-box domain of F-box proteins. /evidence=ECO:0000250	104..163		15/58 (26%)
		Skp1	113..160	CDD:396171	10/49 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S272
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860