Protein Alignment sona and adamts8a

DIOPT Version :10

• Sequence 1: NP_001137746.1
• Gene: sona / 37762
• FlyBaseID: FBgn0034903
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: XP_021332165.1
• Gene: adamts8a / 569618
• ZFINID: ZDB-GENE-060526-202
• Length: 940
• Species: Danio rerio
• Alignment Length: 894
• Identity: 178/894 - (19%)
• Similarity: 301/894 - (33%)
• Gaps: 291/894 - (32%)

  Fly    83 VKKDLSKNAYY--SELKHEALASGGNHLF----APE---------VSAIKSHNVSFSAFGQHLNL 132
            |.:...|..::  .|.:|..|::.| |||    :|:         |..||:.|         |..
Zfish    32 VNRTFRKGLFWRSEERQHFKLSAFG-HLFLLDLSPDSKFVSPVLNVQRIKAKN---------LRS 86

  Fly   133 SLRATQGLFKGAPHQLRMWTVGSEPNATHGLDLQEIVHEQHTSNDVGEVFQDEKNMAAILMRRHM 197
            .|.|::.  .||.....::     |::  |.||::..:       .|.|..:::::.|:.: .|.
Zfish    87 VLDASRS--GGALRDATLY-----PDS--GADLRDCFY-------TGTVNSEKESVVAVSL-CHG 134

  Fly   198 ETGDLIMEGSIGHDLVIKPLPHELSPNPEESH----HIIYKREASAAEGQLSDFAFMEPDDLLAS 258
            ..|..|.:|.   :..|.|   :.|......|    |:|.:|..|.:......|..|:.|.|:..
Zfish   135 IHGTFITQGV---EYFIHP---KASVQTTGKHFPQVHVIKRRAVSNSRTASLVFDQMKVDSLVKE 193

  Fly   259 EKLERLQRRQRRSRRSAPSSPDFEDLNDEDEGALDGEPQVAESRTRSRRQAPYIIYPEVLVIVDY 323
            .||.              ||.| ||.|                ..|::|......|.|.||:.|.
Zfish   194 SKLN--------------SSED-EDSN----------------MRRAKRFVSAARYIETLVVADA 227

  Fly   324 DGYRLHGGDNLQVKRYFISFWNGVDLRYRLLKGPRIRISIAGIIISRGRDATPYLERNRVGRD-A 387
            ...|.:|.   ::|.|.::.   :.:..::...|.::.:::.:::.     ...:|...||.: :
Zfish   228 SMTRFYGD---EIKHYLLTV---MAMAAQVFVHPSLKNAVSLVVVK-----MVVVEDEEVGPELS 281

  Fly   388 IDSAAALTD--MGKYLFR---ERRLPVYDIAVAITKLDMCRRTSAYGECNRGTAGFAYVGGACVV 447
            .:...||.:  |.:.||.   :|....||.|:..|:.|:|    .|.:|:  |.|.|.||..|
Zfish   282 SNGGVALRNFCMWQQLFNPGSQRHPEHYDTAILFTREDIC----GYKDCD--TLGVADVGTMC-- 338

  Fly   448 NKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDGSPPPSYLGGPGAQRC-RWED---GYI 508
                :...|.::||| .|.......:||:||:|...||.|           :.| :|..   |:.
Zfish   339 ----DPKRSCSVIED-NGLQAAFTVSHELGHVLSMPHDDS-----------KNCEKWFGHLYGHT 387

  Fly   509 MSD-LRHTERGFRWSACTVQSFHHFLNGDTATCLHNAPHEDSALGRSLPGTLLSLDAQCRRDRGT 572
            |:. ..|..:...||.|:......|.:.....||.:.|.....|...|||....||.||::..|.
Zfish   388 MAPFFVHLNKTLPWSPCSALYITEFFDNGHGDCLLDPPEMTIPLAAELPGHTFGLDQQCQQAFGN 452

  Fly   573 -YACFKD---ERVCAQLFCFDAQTGYCVAYRPA---AEGSACGNGYHCLDGRC------------ 618
             |....:   ::.|.||:|.:.....|.....:   |:|:.||....|.:|.|
Zfish   453 KYTHCSNAPADQTCVQLWCREEGKIQCTTRNGSLHWADGTPCGEDRRCREGLCLSSAMEEAGEQK 517

  Fly   619 --------------------------------TPLPSNIIPDYGHNY----RLVYNKIDNKKDAA 647
                                            :|:|.|     |..|    |:.|... |.:...
Zfish   518 VPVNGGWGEWGPWGPCSRTCGGGVEFSHRECTSPVPQN-----GGLYCVGQRVKYQSC-NTQTCP 576

  Fly   648 EDVESSSEETESQEDETE-----------------SVEDQD----------------------EG 673
            ||...|..|.:.::..::                 .|..:|                      :|
Zfish   577 EDHGKSFREEQCEKYNSDRYMDIKGNIKQWIPKYSGVSPRDRCKLVCRAKGSNEFKVFEAKVVDG 641

  Fly   674 TTSSEEQ-------------------EDNKIEQSSAAGGAAAQSTTTARSTTTTTVR-----TTS 714
            ||...:.                   .:.|:::.|..||........:.|....|:.     |..
Zfish   642 TTCGPDTTSICVQGQCIKAGCDQVIGSNEKLDKCSVCGGDGTTCRKISGSLNKATIGYIDIVTIP 706

  Fly   715 TTTTTAKPKSKSFGYLHRSLP-ERQWM----QDNGVLVTTRISSSVSSSS----------SGSSS 764
            ...|....|.:|    ||.:| :..::    ||...::....|.|::...          ||||
Zfish   707 AGATNIDIKQRS----HRGIPHDGNYLAVKAQDGTYILNGNFSVSMAEQDVPVPGAMLRYSGSS- 766

  Fly   765 GEAAATSTRRPTTTTTTQTPNLFQI-------------YTHELRKQIEY 800
                 |:..|..:....|.|...|:             ||..|.:.:.:
Zfish   767 -----TTLERLLSFHRLQEPITIQLLSTAGDISPPRIKYTFFLPRDVPF 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sona	NP_001137746.1	ZnMc_salivary_gland_MPs	313..542	CDD:239800	56/239 (23%)
		ADAMTS_CR_2	556..619	CDD:465496	20/113 (18%)
adamts8a	XP_021332165.1	Pep_M12B_propep	44..167	CDD:460254	33/155 (21%)
		ZnMc_ADAMTS_like	217..422	CDD:239801	56/239 (23%)
		ADAMTS_CR_2	436..506	CDD:465496	19/69 (28%)
		TSP1	533..576	CDD:214559	8/48 (17%)
		ADAMTS_CR_3	<619..685	CDD:437068	7/65 (11%)
		ADAMTS_spacer1	687..805	CDD:461796	24/127 (19%)
		TSP1_ADAMTS	832..883	CDD:465950
		TSP1_ADAMTS	886..940	CDD:465950