DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sona and col28a1a

DIOPT Version :9

Sequence 1:	NP_001137746.1	Gene:	sona / 37762	FlyBaseID:	FBgn0034903	Length:	1102	Species:	Drosophila melanogaster
Sequence 2:	NP_001334976.1	Gene:	col28a1a / 555428	ZFINID:	ZDB-GENE-070705-84	Length:	1170	Species:	Danio rerio

Alignment Length:	330	Identity:	57/330 - (17%)
Similarity:	116/330 - (35%)	Gaps:	107/330 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LQSVFHVDTHDAV--PHYELVQLQHHENNHNRRRRSIGKGPKVNAALPPHHVKKDLSK--NAYYS 94
            |:.||.:|:.::|  .:||:|:                  ..||:.:....|.::.::  ...||
Zfish   801 LELVFVIDSSESVGPDNYEVVK------------------DFVNSLIDHVSVSREATRVGVVLYS 847

  Fly    95 ELKHEALASGGNHLFAPEVSAIKS--HNVSFSAFGQHLNLSLRATQGLFKGAPHQLR----MWTV 153
            .:  |.:.:....|:  :.:|:|:  ..:.:...|.....::|....||:.|...:|    :.|.
Zfish   848 HV--EVVVASLQQLY--DQAAVKTAVRRMPYLGEGTFTGSAIRRATQLFQAARPGVRKVAVVLTD 908

  Fly   154 GSEPNATHGLDLQEIVHEQHTSN----DVGEV---------FQDEKNMAAI------------LM 193
            |...| ...:.|::.....|::.    .||.|         |::|.|:.|.            .:
Zfish   909 GLADN-RDAVSLKDAAEGAHSAGIEIFVVGIVNNSDSQYAEFKNEMNILASDPDENYVYLTDDFL 972

  Fly   194 RRHMETGDLI-------------MEGSIGHDLVIKPLPHELSPNPEESHHIIYKREASAAEGQLS 245
            :.|.....|:             ..|...|.....|:|....| |...:.|...:|.:
Zfish   973 KLHALESRLLNHICEHDNGKVFSSSGKTIHPFGPDPVPDRTEP-PTSDYFITEGKEDT------- 1029

  Fly   246 DFAFMEPDDLLASEKLERLQRRQRRSRRSAPSSP-DFEDLNDED---EGALDGEPQVAES--RTR 304
                 .|.|.                 .:.|..| |::|::.:.   :|:::..|.|.|:  ..:
Zfish  1030 -----PPIDF-----------------ETLPQQPEDYDDIHIDTSYFDGSVNEIPWVTETPDGNK 1072

  Fly   305 SRRQA 309
            :|:|:
Zfish  1073 TRQQS 1077

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sona	NP_001137746.1	ZnMc_salivary_gland_MPs	313..542	CDD:239800
col28a1a	NP_001334976.1	vWFA_subfamily_ECM	49..214	CDD:238727
		Collagen	266..339	CDD:189968
		Collagen	311..384	CDD:189968
		Collagen	491..548	CDD:189968
		Collagen	529..590	CDD:189968
		Collagen	561..633	CDD:189968
		Collagen	700..776	CDD:189968
		VWA	803..980	CDD:306576	35/199 (18%)
		Kunitz_BPTI	1117..1168	CDD:278443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900