DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sona and Adamtsl3

DIOPT Version :9

Sequence 1:	NP_001137746.1	Gene:	sona / 37762	FlyBaseID:	FBgn0034903	Length:	1102	Species:	Drosophila melanogaster
Sequence 2:	NP_001177303.1	Gene:	Adamtsl3 / 269959	MGIID:	3028499	Length:	1706	Species:	Mus musculus

Alignment Length:	149	Identity:	38/149 - (25%)
Similarity:	44/149 - (29%)	Gaps:	63/149 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   496 PGAQ---RCRWEDGYIMSDLRHTERGFRWSACTVQSFHHFLNGDTATCLHNAPHED------SAL 551
            ||.|   ||          :.|..|         ...||      ..|.||:...|      .|.
Mouse  1565 PGNQCPGRC----------MGHATR---------MQHHH------TACSHNSSSSDCEDGRRPAF 1604

  Fly   552 GRSLPGTLLSLDAQCRRDRGTYACFKDERVCAQLF------------CFDAQTGYCVAYRPAAEG 604
            ||:.  ||...:| |.|......|   ..||.:.|            |......|||..:|||
Mouse  1605 GRNC--TLGPCEA-CWRVGPWKPC---TAVCGRGFQSRKVDCIHTGSCKIVADRYCVQVKPAA-- 1661

  Fly   605 SACGNGYHCL----DGRCT 619
                 ..|||    |..||
Mouse  1662 -----WRHCLGPSCDRNCT 1675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sona	NP_001137746.1	ZnMc_salivary_gland_MPs	313..542	CDD:239800	10/48 (21%)
Adamtsl3	NP_001177303.1	TSP1	90..136	CDD:214559
		TSP1	438..492	CDD:214559
		TSP1	498..>527	CDD:214559
		TSP1	583..>603	CDD:214559
		TSP1	720..773	CDD:214559
		TSP1	776..833	CDD:214559
		TSP1	839..894	CDD:214559
		Ig	942..1006	CDD:299845
		Ig	1234..1293	CDD:299845
		IG_like	1321..1393	CDD:214653
		IGc2	1330..1388	CDD:197706
		TSP_1	1503..1558	CDD:301595
		PLAC	1674..1704	CDD:285849	2/2 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900