Protein Alignment sona and Adamts18

DIOPT Version :10

• Sequence 1: NP_001137746.1
• Gene: sona / 37762
• FlyBaseID: FBgn0034903
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: XP_006530858.1
• Gene: Adamts18 / 208936
• MGIID: 2442600
• Length: 1253
• Species: Mus musculus
• Alignment Length: 714
• Identity: 177/714 - (24%)
• Similarity: 258/714 - (36%)
• Gaps: 244/714 - (34%)

  Fly    21 GLPDLHKQMTPEQLQSVFHVDTHDAVPHYELVQLQHHENNHNRRRRSIGKGPKVNAALPPHHVKK 85
            ||.|.:..:.|.::.|.....:||.:              |:|:|||
Mouse    91 GLNDDYVFVVPVEVDSGGSYISHDIL--------------HHRKRRS------------------ 123

  Fly    86 DLSKNAYYSELKHEALASGGNHLFAPEVSAIKSHNVSFSAFGQHLNLSLRATQGLFKGAPHQLRM 150
                            |.|          |..|.:...|||||.|:|.|:.:..|   :.| .|:
Mouse   124 ----------------AHG----------ASNSLHYRVSAFGQDLHLELKPSAIL---SSH-FRV 158

  Fly   151 WTVGSE-PNATHGLDLQEIVHEQHTSNDVGEVFQDEKNMAAI--------LMRRHMETGDLIMEG 206
            ..:|.: .:.|...::.:.:::       |.:..|..:..|:        |:|    |.|
Mouse   159 QVLGKDGASETREPEVPQCLYQ-------GFIRNDSSSSVAVSTCAGLSGLIR----TRD----- 207

  Fly   207 SIGHDLVIKPLPHELS-----PNPEESH-HIIYKREASAAEGQLSDF------------AFMEPD 253
               ::.:|.|||..|:     .:|...| |::|||.|........|:            :...|
Mouse   208 ---NEFLISPLPQLLAQEHNYSSPAGHHPHVLYKRTAEKRVRWYQDYPGSQRTYPGHSPSHTPP- 268

  Fly   254 DLLASEKLE------RLQRRQ--RRSRRSAPSSPDFEDLNDEDEGALDGEPQVAESRTRSRRQAP 310
               ||:..|      |.|:|.  .|.::.||..|..:.....||....|.|:      ||..::.
Mouse   269 ---ASQSQEPEYSHRRWQKRHFCGRRKKYAPKPPAEDAYLRFDEYGGTGRPR------RSAGKSQ 324

  Fly   311 YIIYPEVLVIVDYDGYRLHGGDNLQVKRYFISFWNGVDLRYRLLK----GPRIRISIAGIIISRG 371
            ..:..|.||:.|......||.|:  |..|.::..|.|.   .|.|    |..|.|.:..:|:
Mouse   325 NGLNVETLVVADAKMVEKHGKDD--VTTYILTVMNMVS---SLFKDGTIGSDINIVVVSLIL--- 381

  Fly   372 RDATPYLER-------NRVGRDAIDS-----AAALTDMGKYLFRERRLPVYDIAVAITKLDMCRR 424
                  ||.       |.....:::|     :|.:...||.         :|.|:.:|..|:|..
Mouse   382 ------LEEEPEGLLINHHADQSLNSFCQWQSALVGKNGKR---------HDHAILLTGFDICSW 431

  Fly   425 TSAYGECNRGTAGFAYVGGACVVNKRLEKVNSVAIIEDTG-GFSGIIVAAHEVGHLLGAVHDGSP 488
            .:.  .|:  |.|||.:.|.|      .|..|..|.|||| |.:..|  |||.||..|.||||.
Mouse   432 KNE--PCD--TLGFAPISGMC------SKYRSCTINEDTGLGLAFTI--AHESGHNFGMVHDGE- 483

  Fly   489 PPSYLGGPGAQRCRWEDGYIMSDLRHTERG-FRWSACTVQSFHHFLNGDTATCLHNAPHEDSALG 552
                 |.|    ||..:|.|||.......| |.||:|:.|....||:...|.||.:.|.:   .|
Mouse   484 -----GNP----CRKAEGNIMSPTLTGNNGVFSWSSCSRQYLKKFLSTPQAGCLVDEPKQ---TG 536

  Fly   553 R-----SLPGTLLSLDAQCRRDRGTYA--C----FKDERVCAQLFCFDAQTGY-C-VAYRPAAEG 604
            :     .|||.:...|.||:...|..|  |    .||  :|..|:|.  :.|: | ..:.|||||
Mouse   537 QYKYPDKLPGQIYDADMQCKWQFGAKAKLCSLGVMKD--ICKSLWCH--RVGHRCETKFMPAAEG 597

  Fly   605 SACGNGYHCLDGRCT------PLP-----------------------------SNIIPDYGHNY 633
            :|||....|..|:|.      |.|                             ||..|.||..|
Mouse   598 TACGLSMWCRQGQCVKLGELGPRPIHGQWSAWSKWSECSRTCGGGVKFQERHCSNPKPQYGGKY 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sona	NP_001137746.1	ZnMc_salivary_gland_MPs	313..542	CDD:239800	73/246 (30%)
		ADAMTS_CR_2	556..619	CDD:465496	25/70 (36%)
Adamts18	XP_006530858.1	Pep_M12B_propep	99..237	CDD:460254	41/218 (19%)
		ZnMc_ADAMTS_like	327..528	CDD:239801	72/245 (29%)
		ADAMTS_CR_2	545..612	CDD:465496	25/70 (36%)
		TSP1	626..678	CDD:214559	6/36 (17%)
		ADAMTS_CR_3	682..782	CDD:437068
		ADAMTS_spacer1	784..895	CDD:461796
		TSP1_ADAMTS	917..965	CDD:465950
		TSP1_ADAMTS	969..1025	CDD:465950
		TSP1_ADAMTS	1029..1082	CDD:465950
		TSP1_ADAMTS	1090..1149	CDD:465950
		TSP1_ADAMTS	1159..1205	CDD:465950
		PLAC	1220..1250	CDD:462560