Protein Alignment sona and ADAMTS7

DIOPT Version :9

• Sequence 1: NP_001137746.1
• Gene: sona / 37762
• FlyBaseID: FBgn0034903
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: XP_005254194.1
• Gene: ADAMTS7 / 11173
• HGNCID: 223
• Length: 1689
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 144/569 - (25%)
• Similarity: 221/569 - (38%)
• Gaps: 124/569 - (21%)

  Fly    95 ELKHEALASGGNHLFAPEV--SAIKSHNVSF----SAF------GQHLNLSLRATQGLFKGAPHQ 147
            ::.|......|....:.|:  .|::..:||.    .||      |:.|..:|.|.|.|.  ||..
Human    44 DIVHPVRVDAGGSFLSYELWPRALRKRDVSVRRDAPAFYELQYRGRELRFNLTANQHLL--APGF 106

  Fly   148 LRMWTVGSEPNATHGLDLQEIVHEQHTSNDVGEVFQD---EKNMAAILMRRHMETGDLIMEGSIG 209
            :      ||.....||....|.......:.:||| ||   |..:|||          ...:|..|
Human   107 V------SETRRRGGLGRAHIRAHTPACHLLGEV-QDPELEGGLAAI----------SACDGLKG 154

  Fly   210 ------HDLVIKPLPHELSPNPEESHHIIYKREASAAEGQLSDFAFMEPDDLLASEKLERLQRRQ 268
                  .|..|:||....:.......|::|||:|.                          :|..
Human   155 VFQLSNEDYFIEPLDSAPARPGHAQPHVVYKRQAP--------------------------ERLA 193

  Fly   269 RRSRRSAPSS------PDFEDLNDEDEGALD-GEPQVAESRTRSRRQAPYIIYPEVLVIVDYDGY 326
            :|...||||:      |:.|...:..|.... ..|::.....||..:..::   |.||:.|....
Human   194 QRGDSSAPSTCGVQVYPELESRRERWEQRQQWRRPRLRRLHQRSVSKEKWV---ETLVVADAKMV 255

  Fly   327 RLHGGDNLQVKRYFISFWNGV-DLRYRLLKGPRIRISIAGIIISRGRDATPYLERNRVGRDAIDS 390
            ..||  ..||:.|.::..|.| .|.:....|..|.|:|..:::....:     |..::...|.::
Human   256 EYHG--QPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEE-----EDLKITHHADNT 313

  Fly   391 AAALTDMGKYL-FRERRLPV-YDIAVAITKLDMCRRTSAYGECNRGTAGFAYVGGACVVNKRLEK 453
            ..:.....|.: .:....|: :|.|:.:|:.|:|...:...|    |.|.::|.|.|..::
Human   314 LKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCE----TLGLSHVAGMCQPHR---- 370

  Fly   454 VNSVAIIEDTG---GFSGIIVAAHEVGHLLGAVHDGSPPPSYLGG---PGAQRCRWEDGYIMS-D 511
              |.:|.||||   .|:    .|||:||..|..||||      |.   |..:|     .:||| .
Human   371 --SCSINEDTGLPLAFT----VAHELGHSFGIQHDGS------GNDCEPVGKR-----PFIMSPQ 418

  Fly   512 LRHTERGFRWSACTVQSFHHFLNGDTATCLHNAPHEDSALGRSL-PGTLLSLDAQCRRDRGTYAC 575
            |.:......||.|:.|....||:.....||.:.|.:|.....|: ||.|..:..|||...|.|:.
Human   419 LLYDAAPLTWSRCSRQYITRFLDRGWGLCLDDPPAKDIIDFPSVPPGVLYDVSHQCRLQYGAYSA 483

  Fly   576 FKD--ERVCAQLFCFDAQTGYCVAYRPAA-EGSACGNGYHCLDGRCTPL 621
            |.:  :.||..|:|....|  |.:...|| :|:.||....||.|.|.|:
Human   484 FCEDMDNVCHTLWCSVGTT--CHSKLDAAVDGTRCGENKWCLSGECVPV 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sona	NP_001137746.1	ZnMc_salivary_gland_MPs	313..542	CDD:239800	62/238 (26%)
ADAMTS7	XP_005254194.1	Pep_M12B_propep	68..183	CDD:279848	33/133 (25%)
		Reprolysin	242..452	CDD:279729	63/244 (26%)
		ZnMc_ADAMTS_like	242..449	CDD:239801	62/241 (26%)
		ADAM_CR	<474..530	CDD:301627	20/57 (35%)
		TSP1	541..593	CDD:214559
		ADAM_spacer1	699..809	CDD:283607
		TSP1	825..880	CDD:214559
		TSP1	946..994	CDD:214559
		TSP1	1466..1521	CDD:214559
		TSP1	1570..1629	CDD:214559

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810