DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sona and adamtsl5

DIOPT Version :9

Sequence 1:	NP_001137746.1	Gene:	sona / 37762	FlyBaseID:	FBgn0034903	Length:	1102	Species:	Drosophila melanogaster
Sequence 2:	XP_005166548.1	Gene:	adamtsl5 / 101886605	ZFINID:	ZDB-GENE-161017-76	Length:	538	Species:	Danio rerio

Alignment Length:	381	Identity:	82/381 - (21%)
Similarity:	120/381 - (31%)	Gaps:	139/381 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   431 CNRGTAGFA-----------YVGGACVVNKRLEKV-NSVAIIEDTGGFSGIIVAAHEVGHLLGAV 483
            |:|...|.|           .|||.|..:.|..|: ||.....|:..|..:...|.....|:.
Zfish    64 CSRSCGGGASVRTRTCMTRNLVGGPCPGDTRQYKICNSKECPADSMDFRELQCKAFNDRPLVA-- 126

  Fly   484 HDGSPPPSYLGGPGAQRCRWEDGYIMSDLRHTERGFRWSACTVQSFHHFLNGDTATCL---HNAP 545
              ||                              .|.|:     :||...:....:||   ||..
Zfish   127 --GS------------------------------SFHWT-----TFHGGSDPCELSCLAIGHNFY 154

  Fly   546 HEDSALGRSLPGTLLSLDAQCRRDRGTYA----CFK-----------DERVCAQLFCFDAQTGYC 595
            :.   .||.|.||      .|:.|:||..    |.|           .|..|  :.| ......|
Zfish   155 YN---FGRVLDGT------PCQSDQGTVCVNGKCLKPGCDLIFGSQQQEDAC--MVC-GGHNSTC 207

  Fly   596 VAYRPAAEGSACGNGYHCLDG--RCTPLPSNI----IPDYGHNYRLVYN-----------KID-- 641
            :.:|...:.:...||   |.|  ..|.:|:..    :.|...||..:.|           ||:
Zfish   208 LHHRSVYQSNGQNNG---LFGYSEVTMIPAGATHIRVTDNSRNYLALQNGHSQFVINGNWKINVP 269

  Fly   642 ----------NKKDAAEDVESSSEETESQEDETESVEDQDEGTTSSEEQE-------------DN 683
                      ..:.:|:..||......:|||....|...|:  .|..|.|             .:
Zfish   270 GEYSVAGTKLQYRRSADTWESFEVSGPTQEDLHIMVLSTDK--KSGIEYEYWLPPDRYALYHGRS 332

  Fly   684 KIEQSSAAGGAAAQSTTTARSTTTTTVRTTSTTTTTAKPKSKSFGYLHRSLPERQW 739
            ::.|:............|.|:|||       ||||||:|.:::|.:    .|..||
Zfish   333 QLRQTHHTANHLPFEPPTTRTTTT-------TTTTTAQPTTRAFFW----GPAAQW 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sona	NP_001137746.1	ZnMc_salivary_gland_MPs	313..542	CDD:239800	24/125 (19%)
adamtsl5	XP_005166548.1	TSP1	55..105	CDD:214559	12/40 (30%)
		ADAM_spacer1	219..321	CDD:283607	23/106 (22%)
		NTR	426..519	CDD:280015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900