Protein Alignment sona and adamts3

DIOPT Version :10

• Sequence 1: NP_001137746.1
• Gene: sona / 37762
• FlyBaseID: FBgn0034903
• Length: 1102
• Species: Drosophila melanogaster
• Sequence 2: XP_012810820.2
• Gene: adamts3 / 100498276
• XenbaseID: XB-GENE-490472
• Length: 1199
• Species: Xenopus tropicalis
• Alignment Length: 579
• Identity: 140/579 - (24%)
• Similarity: 214/579 - (36%)
• Gaps: 144/579 - (24%)

  Fly   106 NH--LFAPEVSAIKSHNVSF--SAFGQHLNLSLRATQGLFKGAPHQLRMWTVGSEPNATHGLDLQ 166
            ||  .|..:.|.:: |.:.|  :|||:..:|.||....|.  ||..:..|. ..:.|.|:|..
 Frog    65 NHKKRFTRDTSQVQ-HTLYFNVTAFGREFHLKLRPNTKLI--APGAVIEWH-EDQVNLTNGFH-- 123

  Fly   167 EIVHEQHTSND-----------------VGEVFQDEKNMAAIL-------MRRHMETGDLIMEGS 207
              ...|:..||                 |||:......:.|:.       |.|..|
 Frog   124 --TGNQNPDNDTAHQIWRKESLWTNCAYVGEITDSPGALVALSNCDGLAGMIRTKE--------- 177

  Fly   208 IGHDLVIKPLPHELSPNPEESH-HIIYKREAS--AAEGQLSDFAFMEPDDLLASEKLERLQRRQR 269
              .:..|:||......:.|... |::|||..:  ...|...:|
 Frog   178 --DEYFIEPLERGKQKDEENGRLHVVYKRSTAKQIPTGDSHNF---------------------- 218

  Fly   270 RSRRSAPSSPDFEDLNDEDEGALDGEPQVAESRTRSRRQAPYIIYPEVLVIVDYDGYRLHGGDNL 334
                   |..||..|::.|....:.|.||.|:..|.|.........|||:.||....|.||.:::
 Frog   219 -------SEADFAGLDNVDSIFSNIEKQVNETLRRRRHAGENDYNIEVLLGVDDSVVRFHGKEHV 276

  Fly   335 QVKRYFISFWNGVDLRYRLLK-GPRIRISIAGIIISRGRDATPYLERNRVGRDAIDSAAALTDMG 398
            |  .|.::..|.|:..|.... |..|.|.:..:|:.....:...:||....|       :|.::.
 Frog   277 Q--NYLLTLMNIVNEIYHDDSIGVHINIVLVRMIMLGYAKSISLIERGSPSR-------SLDNVC 332

  Fly   399 KYLFRERRLPV-----YDIAVAITKLDMCRRTSAYGECNRGTAGFAYVGG------ACVVNKRLE 452
            ::..::::...     :|.|:.:|:.|       :|..  |..|:|.|.|      :|.:|.
 Frog   333 RWASQQQKADPNHSEHHDHAIFLTRQD-------FGPA--GMQGYAPVTGMCHPMRSCTLNH--- 385

  Fly   453 KVNSVAIIEDTGGFSGIIVAAHEVGHLLGAVHDGSPPPSYLGGPGAQRCRWED--GYIMSDL-RH 514
                    ||  |||...|.|||.||:||..|||.          ..||..|.  |.:|:.| :.
 Frog   386 --------ED--GFSSAFVVAHETGHVLGMEHDGQ----------GNRCGDETAMGSVMAPLVQA 430

  Fly   515 TERGFRWSACTVQSFHHFLNGDTATCLHNAPHE-DSALGRSLPGTLLSLDAQCRRDRGT----YA 574
            ....:.||.|:.|....:::  :..||.:.|.| |......|||...|:|.|||.|.|.    ..
 Frog   431 AFHRYHWSRCSGQELKRYIH--SYDCLLDDPFEHDWPKLPDLPGINYSMDEQCRFDFGVGYKMCT 493

  Fly   575 CFKDERVCAQLFCFDAQTGY-CVAYR-PAAEGSACGNGYHCLDGRCTPLPSNIIPDYGH 631
            .|:....|.||:|......| |...: |..:|:.|..|..|..|.|....:|.:...|:
 Frog   494 AFRTFEPCKQLWCNHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKTTNQVKQDGN 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sona	NP_001137746.1	ZnMc_salivary_gland_MPs	313..542	CDD:239800	60/243 (25%)
		ADAMTS_CR_2	556..619	CDD:465496	22/68 (32%)
adamts3	XP_012810820.2	Pep_M12B_propep	44..202	CDD:460254	34/155 (22%)
		ZnMc_ADAMTS_like	255..456	CDD:239801	60/243 (25%)
		ADAMTS_CR_2	471..539	CDD:465496	22/67 (33%)
		TSP1	553..605	CDD:214559	140/579 (24%)
		ADAMTS_CR_3	610..711	CDD:437068
		ADAMTS_spacer1	713..826	CDD:461796
		TSP1_ADAMTS	848..903	CDD:465950
		TSP1_ADAMTS	908..965	CDD:465950
		TSP1_ADAMTS	969..1014	CDD:465950
		PLAC	1022..1050	CDD:462560