Protein Alignment egl and Exd1

DIOPT Version :9

• Sequence 1: NP_001286779.1
• Gene: egl / 37757
• FlyBaseID: FBgn0000562
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_766445.1
• Gene: Exd1 / 241624
• MGIID: 3045306
• Length: 570
• Species: Mus musculus
• Alignment Length: 619
• Identity: 126/619 - (20%)
• Similarity: 231/619 - (37%)
• Gaps: 168/619 - (27%)

  Fly   436 VNQTLKQRINTLVIRTLAE----NLEKDK----QSLANQQGGPISPHASPV--HSIANSSSNQNA 490
            :||.|.:|:...::..:.|    :::.:|    :::.|.:.|...|.....  |.|.|......|
Mouse    10 LNQILWRRVKLTLVSGIFEGVLQHVDPNKIVVLKNVRNAESGRSVPGVKVFFGHEILNVELMDEA 74

  Fly   491 GSAANNANSNSNANPNNANHSPSHSYFVGDTWKIK-----VLQNTTVIANVKQSVFVTDIILKYA 550
            ..|:....|..:.|...|...           |:|     |.:..:....|..|..::|  |||.
Mouse    75 EGASGEKASAVSINTERAGME-----------KVKNEDVNVCEPASPAPEVPTSSLLSD--LKYC 126

  Fly   551 AKNE------------------------SIVVSLDCEGINLGLKGEITLIEIGTTRGEAFLFDVQ 591
            ...|                        ..|:|:..||.|:...|::..::: .|....:|||:.
Mouse   127 PSEEEEVTYTVIDQFQQKFGAAMLHIKKQSVLSVAAEGANVCRHGKLCWLQV-ATNSRVYLFDIF 190

  Fly   592 SCPAMVTDGGLKTVLEHDQVIKVIHDCRNDAANLYLQFGILLRNVFDTQAAHAILQY-------- 648
            ...:...:.||:.:||..:::|||||||..:..|..|:||:|.||||||.|. :||:
Mouse   191 LLGSRAFNNGLQMILEDKRILKVIHDCRWLSDCLSHQYGIMLNNVFDTQVAD-VLQFSMETGGFL 254

  Fly   649 -------QESGKQVYKA--KYISLNSLCEQYNAPCNPIKDQLKQIYRRDQKFWAKRPLTREMMLY 704
                   |||..:..|.  :|:..             ::::.|:| :.:.:.|..|||...::..
Mouse   255 PNCISTLQESLIRHLKVAPRYLFF-------------LEERQKRI-QENPEIWLTRPLPPSLLKI 305

  Fly   705 AAGDV-------LVLIHDQLFGNLA----------RQIKPENRALFSELCTEQILMQIKPNEVKI 752
            .|.:.       |||: |::..:|.          |:...:..|.....|.|.....::..:.:.
Mouse   306 LALETTYLLPLRLVLL-DEVMSDLTTLVDGYLNTYREGSADRLAGTEPACMELPAELLQLQDFQK 369

  Fly   753 RKKQRKVSTEVSDLKQKLAQTSKSIVLSNREIRLLRYMDLTEDEKERLKG--YYK---------- 805
            ::::|.|.....:.:..|.:|.    |..:|...     .|..::||::|  :||
Mouse   370 QRRERAVKEYRVNARGLLIRTP----LHPKEPTA-----CTAGKEERVQGFLFYKTDGGDQVPRF 425

  Fly   806 VAKKLEKMESAGNPSKDQSDSEDEQEP--NENDAFPSLDSVPSDNSLSGTFSPRFSSE---PP-- 863
            :..|..:.|...:....|:.::.:..|  .|.:|.....:.|.....:|...||....   ||
Mouse   426 LCPKSHEDEKFLDKESKQTTAKSQIVPPRKEGEAHKDSKNKPGCWESAGPEDPRAQKAHALPPTW 490

  Fly   864 ------SLTESMQMLEEILQNKSMDRIARIDKLEAILTTATSLPCEQIIASNSMQEQLGSSIATT 922
                  ||.|.::.| .::.||.                |.:.|.|..:.|.|:.::...:...|
Mouse   491 ASQSQFSLKEEIEQL-TVVGNKG----------------ALTSPKEGALVSPSLLQETWEAPTDT 538

  Fly   923 ENLQIIREKSK--NIKNCNCQGERSVTPIMRTTD 954
            .:|.   ||::  .:..|         |.:..||
Mouse   539 FHLP---EKAEVSTLPPC---------PALEKTD 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
egl	NP_001286779.1	Egl_like_exo	541..744	CDD:99851	61/260 (23%)
Exd1	NP_766445.1	Egl_like_exo	146..344	CDD:99851	53/214 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	433..485		9/51 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841507
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8098
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003633
OrthoInspector	1	1.000	-	-		oto91954
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3677
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.770