Protein Alignment CG18128 and PNP

DIOPT Version :9

• Sequence 1: NP_611822.1
• Gene: CG18128 / 37756
• FlyBaseID: FBgn0034898
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_000261.2
• Gene: PNP / 4860
• HGNCID: 7892
• Length: 289
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 104/281 - (37%)
• Similarity: 154/281 - (54%)
• Gaps: 6/281 - (2%)

  Fly    45 YPFEEVEAMAKYIVNVSHIRPKYGLICGSFLSDMVSLVEQPVVIPYEDIPNFPDGIEPDCS--FV 107
            |.:|:.:..|:::::.:..||:..:||||.|..:...:.|..:..|.:|||||....|..:  .|
Human     5 YTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRSTVPGHAGRLV 69

  Fly   108 LGTVMGAPIIALVHSFHSCDGYNLATCALPVRVMQLCGVRTIMLTSEAAAVDHGFALGDIMLVQD 172
            .|.:.|...:.:...||..:||.|.....||||..|.||.|:::|:.|..::..|.:|||||::|
Human    70 FGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRD 134

  Fly   173 HINVVGMMHQTPLEGPSDPRFGSRRFSMVNAYDKDLLEKALEIGKRMGIQKFLHSGVLACMGGPI 237
            |||:.|...|.||.||:|.|||.|..:|.:|||:.:.::||...|:||.|:.|..|....:.||.
Human   135 HINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQMGEQRELQEGTYVMVAGPS 199

  Fly   238 LGTVAEERMLRTMEVSAVGMSLVPEVIAAHHGGLKVLAF-VVISRAASDKESEESDKDKEKDTDR 301
            ..||||.|:|:.:...|||||.|||||.|.|.||:|..| ::.::...|.||.|....:|.....
Human   200 FETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAG 264

  Fly   302 DSKQDKREQ---DSQEPVPLP 319
            .....|.||   .....:|||
Human   265 KQAAQKLEQFVSILMASIPLP 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18128	NP_611822.1	PNP_UDP_1	46..280	CDD:294213	92/236 (39%)
		XapA	50..280	CDD:223084	91/232 (39%)
PNP	NP_000261.2	PNPH	26..280	CDD:273764	96/253 (38%)
		Phosphate binding. /evidence=ECO:0000269|PubMed:23438750, ECO:0000305|PubMed:14706628, ECO:0000305|PubMed:1763067, ECO:0007744|PDB:1RCT, ECO:0007744|PDB:1ULA, ECO:0007744|PDB:1ULB, ECO:0007744|PDB:1V3Q, ECO:0007744|PDB:4EAR, ECO:0007744|PDB:4EB8, ECO:0007744|PDB:4GKA	84..86		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147140
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0005
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S669
OMA	1	1.010	-	-		QHG58962
OrthoDB	1	1.010	-	-		D1078969at2759
OrthoFinder	1	1.000	-	-		FOG0001804
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11904
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.770