DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sesn and Sesn3

DIOPT Version :9

Sequence 1:	NP_001097437.1	Gene:	Sesn / 37755	FlyBaseID:	FBgn0034897	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001101595.1	Gene:	Sesn3 / 315427	RGDID:	1309470	Length:	492	Species:	Rattus norvegicus

Alignment Length:	500	Identity:	211/500 - (42%)
Similarity:	299/500 - (59%)	Gaps:	81/500 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 AATQTGASDFDMDELDD---LDQVTQVIGYHPQFHDHFLATQNFIMKGDGPLPNDYRYYLAIIAA 81
            |.|....::|.::|...   ||.:|||:..|.|:.:.||.:|.::::.|||||...|:|:||:||
  Rat    52 ANTADERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPDRHYIAIMAA 116

  Fly    82 ARHQCPYLVKRYEKEFINQGGDSAWLGGLDFIPAKLRAIYDINKILAHRPWLLRKEHIERLTK-G 145
            |||||.||:..:..||:..||.:.||.||:::|.:||.:.:|||:|||||||:.||||::|.| |
  Rat   117 ARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLRNLNEINKLLAHRPWLITKEHIQKLVKTG 181

  Fly   146 KNSWSLSEVVHAMVLLSHFHSLSSFVFSCGLTQKLDGLSSPKLKSPPAAVAALAPTILITPTSPT 210
            :|:|||.|:|||:|||:|:|:|:|||:..|:
  Rat   182 ENNWSLPELVHAVVLLAHYHALASFVYGSGI---------------------------------- 212

  Fly   211 EPQKGKPVLAEISLNNANPDYDSQTA-----ASSNGGAPPDSANAVADGPDATTLNGYLATAQQL 270
                             ||:.|...|     .|.:.....|.||..:.| :|:...|.......|
  Rat   213 -----------------NPERDPGIANGFRLISVSSFCVCDLANDNSIG-NASLAGGNFGIVDSL 259

  Fly   271 PQQHGISVETLMERMKVLSQ--KQDECSEAELSSRFQKVEQQTAELAAVTPEAAVGVP------- 326
            .:     :|.||||||.|.:  :.:|.:..|:|:||:|.::::  |..|..|.....|
  Rat   260 GE-----LEALMERMKRLQEDREDEETTPEEMSTRFEKEKKES--LFVVPGETFHSFPHSDFEDD 317

  Fly   327 ----TNLSHYVDDANFIYQDFARRGTESINTFRIQDYSWEDHGYSLVDGLYNDVGIFLDAKFRAA 387
                .::|.|::|..|.|:||||||.|.:.|||.|||:||:||:|||:.||:|:|..||.|||..
  Rat   318 MIVTADVSRYIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMV 382

  Fly   388 YNLTYCTMGGIKNVDTSKFRRAIWNYIQCIYGIRHDDYDYGEVNQLLVRPLKMFIKTACCFPERI 452
            |||||.||...::|||:..|||::||:.|::|||:||||||||||||.|.||::|||..|:|||.
  Rat   383 YNLTYNTMATHEDVDTTTLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPERT 447

  Fly   453 TTKDYDSVLVELQDSEKVHVNLMIMEARNQAELLYALREIMRYMT 497
            |.:.|||...:...||||||||::||||.|||||||||.|.|::|
  Rat   448 TKRMYDSYWRQFTHSEKVHVNLLLMEARMQAELLYALRAITRHLT 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sesn	NP_001097437.1	PA26	4..496	CDD:282488	210/497 (42%)
Sesn3	NP_001101595.1	PA26	39..490	CDD:282488	209/496 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354482
Domainoid	1	1.000	404	1.000	Domainoid score	I700
eggNOG	1	0.900	-	-		E1_KOG3746
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14386
Inparanoid	1	1.050	406	1.000	Inparanoid score	I1835
OMA	1	1.010	-	-		QHG55065
OrthoDB	1	1.010	-	-		D385556at33208
OrthoFinder	1	1.000	-	-		FOG0001796
OrthoInspector	1	1.000	-	-		otm45232
orthoMCL	1	0.900	-	-		OOG6_103913
Panther	1	1.100	-	-	O	PTHR12474
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1152
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770