DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sesn and sesn4

DIOPT Version :9

Sequence 1:	NP_001097437.1	Gene:	Sesn / 37755	FlyBaseID:	FBgn0034897	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	XP_009289447.1	Gene:	sesn4 / 100149048	ZFINID:	ZDB-GENE-160114-34	Length:	444	Species:	Danio rerio

Alignment Length:	467	Identity:	190/467 - (40%)
Similarity:	258/467 - (55%)	Gaps:	77/467 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LDQVTQVIGYHPQFHDHFLATQNFIMKGDGPLPNDYRYYLAIIAAARHQCPYLVKRYEKEFINQG 101
            ||:|:|.:..|||:.:.||.||::|:..|||||..||:|:||:|||||.|.|||..:..:|:..|
Zfish    46 LDKVSQQMASHPQYLESFLRTQHYILYMDGPLPLPYRHYIAIMAAARHHCRYLVSLHSAQFLRVG 110

  Fly   102 GDSAWLGGLDFIPAKLRAIYDINKILAHRPWLLRKEHIERLTK-GKNSWSLSEVVHAMVLLSHFH 165
            ||..||.||:..||:||.:..|||:|||:|||..:.||:.|.| |:..|||:|:|.|:|||:|.|
Zfish   111 GDPLWLQGLEAAPARLRHLDHINKVLAHQPWLTARSHIQALLKTGEQCWSLAELVQAVVLLAHCH 175

  Fly   166 SLSSFVFSCGLTQKLDGLSSPKLK--SPPAAV---AALAPTILITPTS-PTEPQKGKPVLAEISL 224
            ||.||||..|  ...|..::|::.  :||...   ||...|.|..|:| |.|     .:|...||
Zfish   176 SLCSFVFGSG--SDSDITTTPRVHHGTPPGCCLCDAANGNTALSPPSSGPME-----KMLRRRSL 233

  Fly   225 NNANPDYDSQTAASSNGGAPPDSANAVADGPDATTLNGYLATAQQLPQQHGISVETLMERMKVLS 289
            :::                                                ..|..|.|:   :.
Zfish   234 DSS------------------------------------------------CDVGCLREQ---IH 247

  Fly   290 QKQDECSEAELSSRFQKVEQQTAELAAVTPEAAVGVPTNLSHYVDDANFIYQDFARRGTESINTF 354
            :.|||..|    .:..::..||...:.|..|......|:.|.:|.|..|.||:||||..:.....
Zfish   248 KSQDEIKE----RKGDRLHSQTLLHSDVEEEEEAMFSTDPSRFVTDPEFGYQEFARREEDHFQVL 308

  Fly   355 RIQDYSWEDHGYSLVDGLYNDVGIFLDAKFRAAYNLTYCTMGGIKNVDTSKFRRAIWNYIQCIYG 419
            |:|||||||||:|||:.||:|:|..||.:||...:|.:        ..:...:|||||||.||||
Zfish   309 RVQDYSWEDHGFSLVNRLYSDIGHLLDERFRNVASLPF--------PHSPDLKRAIWNYIHCIYG 365

  Fly   420 IRHDDYDYGEVNQLLVRPLKMFIKTACCFPERITTKDYDSVLVELQDSEKVHVNLMIMEARNQAE 484
            ||:|||||||||:||.|.||::||...|:|:...|.........::.||||||||::||||.|||
Zfish   366 IRYDDYDYGEVNRLLERGLKLYIKAVACYPDSSKTPLCPLSWTPVKASEKVHVNLLVMEARLQAE 430

  Fly   485 LLYALREIMRYM 496
            ||||||.|.:||
Zfish   431 LLYALRAITQYM 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sesn	NP_001097437.1	PA26	4..496	CDD:282488	188/465 (40%)
sesn4	XP_009289447.1	PA26	19..442	CDD:282488	188/465 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596797
Domainoid	1	1.000	385	1.000	Domainoid score	I774
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55065
OrthoDB	1	1.010	-	-		D385556at33208
OrthoFinder	1	1.000	-	-		FOG0001796
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12474
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1152
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.960