DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg3 and ALG3

DIOPT Version :9

Sequence 1:	NP_523829.2	Gene:	Alg3 / 37754	FlyBaseID:	FBgn0011297	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_182297.1	Gene:	ALG3 / 819388	AraportID:	AT2G47760	Length:	438	Species:	Arabidopsis thaliana

Alignment Length:	450	Identity:	173/450 - (38%)
Similarity:	248/450 - (55%)	Gaps:	65/450 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LLEPAALPIVGLFVLLAELVINVVVIQRVPYTEIDWVAYMQECEGFLNGTTNYSLLRGDTGPLVY 103
            |.:..|:|. ...::||:.::..::|..||||:|||.|||.:..|||.|..:|..|:||||||||
plant    27 LFKKPAVPF-AFALILADAILVALIIAYVPYTKIDWDAYMSQVSGFLGGERDYGNLKGDTGPLVY 90

  Fly   104 PAAFVYIYSALYYVTSHGTNVRLAQYIFAGIYLLQLALVLRLYSKSRKVPPYVLVLSAFTSYRIH 168
            ||.|:|:|||:..:|  |..|..||.:|..:|::.|.:||.:|.|:..||.:.|.|... |.|||
plant    91 PAGFLYVYSAVQNLT--GGEVYPAQILFGVLYIVNLGIVLIIYVKTDVVPWWALSLLCL-SKRIH 152

  Fly   169 SIYVLRLFNDPVAVLLLYAALNLFLDRRWTLGSTFFSLAVGVKMNILLFAPALLLFYLANLGLLR 233
            ||:|||||||..|:.||:|::.|||.|:|.||...||.||.||||:||:||.|||..|..:.::.
plant   153 SIFVLRLFNDCFAMTLLHASMALFLYRKWHLGMLVFSGAVSVKMNVLLYAPTLLLLLLKAMNIIG 217

  Fly   234 TILQLAVCGVIQLLLGAPFLLTHPVEYLRGSFDLGRIFEHKWTVNYRFLSRDLFENRTFHVSLLG 298
            .:..||...::|:|:|.|||:|:||.|:..:|||||:|.|.|:||::|:...:|.::.|.|.||.
plant   218 VVSALAGAALVQILVGLPFLITYPVSYIANAFDLGRVFIHFWSVNFKFVPERVFVSKEFAVCLLI 282

  Fly   299 LHLLLLLAFAKPTWTFFQ----SYVRLRRIEDQLQPQIAQQNLELNAQKRPKKVEKDKDKDQKKF 359
            .||.||:|||...|...:    .::|.|.....|...::                 ..|....:.
plant   283 AHLFLLVAFANYKWCKHEGGIIGFMRSRHFFLTLPSSLS-----------------FSDVSASRI 330

  Fly   360 TTEQQSFLKAFEKSLQKASGGKATPAPAQAEPERYGIHFDRCTQLALLPFFLCNLVGVACSRSLH 424
            .|::.                                        .:...|:.|.:|:..:||||
plant   331 ITKEH----------------------------------------VVTAMFVGNFIGIVFARSLH 355

  Fly   425 YQFYVWYFHSLPYLAWSTPYSLGVRCLILGLIEYCWNTYPSTNFSSAALHFTHIILLAGV 484
            ||||.|||:|||||.|.||:...:|.::...||.|||.||||..||..|...|:|:|.|:
plant   356 YQFYSWYFYSLPYLLWRTPFPTWLRLIMFLGIELCWNVYPSTPSSSGLLLCLHLIILVGL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg3	NP_523829.2	ALG3	51..470	CDD:282992	163/422 (39%)
ALG3	NP_182297.1	ALG3	37..401	CDD:282992	163/423 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	326	1.000	Domainoid score	I266
eggNOG	1	0.900	-	-		E1_KOG2762
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4228
Inparanoid	1	1.050	337	1.000	Inparanoid score	I657
OMA	1	1.010	-	-		QHG53696
OrthoDB	1	1.010	-	-		D774318at2759
OrthoFinder	1	1.000	-	-		FOG0004953
OrthoInspector	1	1.000	-	-		oto3442
orthoMCL	1	0.900	-	-		OOG6_103036
Panther	1	1.100	-	-	LDO	PTHR12646
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3495
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840