DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment angel and angel1

DIOPT Version :9

Sequence 1:	NP_477204.1	Gene:	angel / 37748	FlyBaseID:	FBgn0016762	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_021328890.1	Gene:	angel1 / 569547	ZFINID:	ZDB-GENE-111020-12	Length:	667	Species:	Danio rerio

Alignment Length:	302	Identity:	97/302 - (32%)
Similarity:	140/302 - (46%)	Gaps:	54/302 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 RRWTSLG--NQAEGRDPHKCSSFKVVSYNILAQDLLLEHLFLYVGIPHEFLSWQRRQQNLLRELL 110
            |.|..|.  ..::..|......|.|:||||||||||..:..||.....:.|.|:.|.|.:|:||.
Zfish   238 RVWEDLSEPQSSDSADASPVFDFSVMSYNILAQDLLEANPHLYTHCAEDALRWENRLQAVLKELQ 302

  Fly   111 KLDPDILCLQEMQFDHL-----PVLVQRLRMGNGKKLAYVYKKKTGCRTDGCAIVYDSSKFELLD 170
            ...|||:||||:|.||.     |||:   .||    ...:||::||.:|||||::|...:|..|.
Zfish   303 IWQPDIVCLQEVQEDHFQEQMHPVLI---NMG----YTCIYKRRTGSKTDGCAVLYRGERFTQLS 360

  Fly   171 HQAVELYDQAVALLNRDNVALFARFR-FKKQQEQQKEFVVATTHLLFNTKRSDVRCAQ------- 227
            ...:|.......||:||||.:....: ......|.....||.||||||.:|.||:.||
Zfish   361 VSLLEFRRSECELLDRDNVGIVLLLQPTAGPHHQFTPVCVANTHLLFNPRRGDVKLAQLAIMFAE 425

  Fly   228 VERILEELQSFSTDTPIVLTGDFNSLPDSSPIEFLVGKNGDVDSTACPEPLHFEIIDSGEGTAST 292
            :..::::.:|......::|.||||::|.|                    || :.:|.:||    .
Zfish   426 IHSVMQKCRSEGKSCELILCGDFNAVPRS--------------------PL-WTLITTGE----L 465

  Fly   293 YQN---EWVIVDYILRSLGSRSRHKLL--PLSVYSLPSINRC 329
            |.:   .|::...  ..|..::.|..|  ||...||...:||
Zfish   466 YYHGLPTWMVSGQ--TDLSYKAHHNRLFSPLWPSSLGITDRC 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
angel	NP_477204.1	EEP	70..351	CDD:294334	92/278 (33%)
angel1	XP_021328890.1	EEP	262..662	CDD:321002	92/278 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576693
Domainoid	1	1.000	129	1.000	Domainoid score	I5222
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D395901at33208
OrthoFinder	1	1.000	-	-		FOG0002618
OrthoInspector	1	1.000	-	-		otm25767
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12121
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3577
SonicParanoid	1	1.000	-	-		X1517
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840