DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment angel and cnot6b

DIOPT Version :9

Sequence 1:	NP_477204.1	Gene:	angel / 37748	FlyBaseID:	FBgn0016762	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001103498.1	Gene:	cnot6b / 560386	ZFINID:	ZDB-GENE-071004-97	Length:	558	Species:	Danio rerio

Alignment Length:	407	Identity:	98/407 - (24%)
Similarity:	155/407 - (38%)	Gaps:	116/407 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KEMESSHDRNRRWTSLGNQAEGRDPHKCSSFKVVSYNILAQDLLLEHLFLYVGIPHEFLSWQRRQ 102
            |.:.:.....|.|..|......|   ..:...|:.||:|........|:.|  .|...|:|..|:
Zfish   162 KRIPTEQPPPRSWIVLQEPERSR---PTALLTVMCYNVLCDKYATRQLYGY--CPSWALNWSYRK 221

  Fly   103 QNLLRELLKLDPDILCLQEMQ----FDHLPVLVQRLRMG-----NGKKLAYVYKKKTGCRTDGCA 158
            :::::|:|..:.||:.|||::    ||..  |::..:.|     :.|..|....:......||||
Zfish   222 KSIMQEILNCNADIISLQEVETEQYFDFF--LLELSKQGYDGFFSPKSRARTMSESDRKHVDGCA 284

  Fly   159 IVYDSSKFELLDHQAVELYDQAV-------ALLNR----DNVALFARFRFKKQ------------ 200
            |.|.:.||.::....||....|:       |:|||    ||:.:......||:
Zfish   285 IFYKTEKFNVVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELKKELIEVSSGKSIHP 349

  Fly   201 QEQQKEFVVATTHLLFNTKRSDVRCAQVERILEELQ-------------SFSTDT---PIVLTGD 249
            .|:|. .:||..|:.::.:.|||:..|....|.|::             |.|.:|   |:||..|
Zfish   350 MEKQL-LLVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRSLKHSSVSGETSSIPLVLCAD 413

  Fly   250 FNSLPDSSPIEFLVGKNGDVD------------------------STACPEPLH-FEIIDSGEGT 289
            .||||||..:|:|  ..|.||                        ||:.....| |::..:.|..
Zfish   414 LNSLPDSGVVEYL--STGGVDCTHKDFKELRYSDSLTNFNCNGKNSTSNGRITHAFKLKSAYENG 476

  Fly   290 ASTYQNEWV----IVDYILRSLGSRSRHKLLPLSVYSLPSINRCIGAGQI-------------PN 337
            ...|.|...    ::|||.                ||.|.:|.....|.:             |:
Zfish   477 LMPYTNYTFDFRGVIDYIF----------------YSRPQLNVLGVLGPLDTNWLLENNISGCPH 525

  Fly   338 YRLGSDHYALGAVFTVV 354
            ..:.|||::|.|...:|
Zfish   526 PLIPSDHFSLFAQLELV 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
angel	NP_477204.1	EEP	70..351	CDD:294334	92/370 (25%)
cnot6b	NP_001103498.1	LRR_8	51..109	CDD:290566
		LRR_4	51..91	CDD:289563
		leucine-rich repeat	53..75	CDD:275380
		LRR_4	75..113	CDD:289563
		leucine-rich repeat	76..98	CDD:275380
		leucine-rich repeat	99..121	CDD:275380
		Deadenylase_CCR4a	191..541	CDD:197340	92/372 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576691
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840