DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment angel and Lrrc27

DIOPT Version :9

Sequence 1:	NP_477204.1	Gene:	angel / 37748	FlyBaseID:	FBgn0016762	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001137228.1	Gene:	Lrrc27 / 499281	RGDID:	1559981	Length:	513	Species:	Rattus norvegicus

Alignment Length:	151	Identity:	30/151 - (19%)
Similarity:	58/151 - (38%)	Gaps:	21/151 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 WQRRQQNLLRELLKLDPDILCLQEMQFDHLPVLVQRLRMGNGKKLAYVYKKKTGCRTDGCAIVYD 162
            |..:::  :|...||..:|:..::::.....:|...| ..|.|  |.:..|:..||.....:...
  Rat   247 WPSKEE--IRRFWKLRQEIVENEQVEVQENKLLAVEL-PPNLK--AAINAKERKCRKPWPTLRKR 306

  Fly   163 SSKFELLDHQAVELYDQAVALLNRDNVALFARFRFKKQQEQQKEFVVATTHLLFNTKRSDVRCAQ 227
            |:.|..:.......|...|.....|:....|   |::.||:::         :...:|.|.|..|
  Rat   307 STSFRGILPNLSSTYQNTVHTKRMDDTHKMA---FQELQEKER---------MLEQQRRDKRALQ 359

  Fly   228 VER----ILEELQSFSTDTPI 244
            ..|    ::...:.||...|:
  Rat   360 DWREQTQLMRHRREFSKFQPL 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
angel	NP_477204.1	EEP	70..351	CDD:294334	30/151 (20%)
Lrrc27	NP_001137228.1	PLN00113	30..>173	CDD:215061
		leucine-rich repeat	50..69	CDD:275378
		LRR_8	68..127	CDD:404697
		leucine-rich repeat	70..93	CDD:275378
		leucine-rich repeat	94..116	CDD:275378
		leucine-rich repeat	117..139	CDD:275378
		leucine-rich repeat	140..151	CDD:275378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900