DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment angel and Noct

DIOPT Version :9

Sequence 1:	NP_477204.1	Gene:	angel / 37748	FlyBaseID:	FBgn0016762	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_612535.1	Gene:	Noct / 310395	RGDID:	1587344	Length:	428	Species:	Rattus norvegicus

Alignment Length:	312	Identity:	89/312 - (28%)
Similarity:	142/312 - (45%)	Gaps:	49/312 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 CSS----FKVVSYNILAQDLLLEHLFLYVGIPHEFLSWQRRQQNLLRELLKLDPDILCLQEMQ-- 123
            |||    .:|:.:||||| .|.|....:|..|.|.|.|:.|:..:|.|:|...||||||||:.
  Rat   133 CSSSHPPIRVMQWNILAQ-ALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHY 196

  Fly   124 FDHLPVLVQRLRMGNGKKLAYVYKKKTGC-------RTDGCAIVYDSSKFELLDHQAVELYDQAV 181
            ||....|:.||    |.:..:..|..:.|       ..||||:.:..|:|:|::...:.|   ..
  Rat   197 FDTFQPLLSRL----GYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQSRFKLINSTNIRL---TA 254

  Fly   182 ALLNRDNVALFARFRFKKQQEQQKEFVVATTHLLFNTKRSDVRCAQVERILEELQSFS--TDTPI 244
            ..|..:.||:......|   |..::|.:|.|||...|.....|.||...:|:.||:.:  ...|:
  Rat   255 MTLKTNQVAIAQTLECK---ESGRQFCIAVTHLKARTGWERFRSAQGCDLLQNLQNITEGAKIPL 316

  Fly   245 VLTGDFNSLPDSSPIEFLVGKNGDVDSTACPEPLHFEIIDSGEGTASTYQNEWVI---------V 300
            ::.||||:.|.....:.....:.:::|.       :::: |.:|.:......|.|         :
  Rat   317 IVCGDFNAEPTEEVYKHFASSSLNLNSA-------YKLL-SPDGQSEPPYTTWKIRTSGECRHTL 373

  Fly   301 DYILRSLGSRSRHKLLPLSVYSLPSINRCIGAGQIPNYRLGSDHYALGAVFT 352
            |||.     .|||.|...|...|.:..: ||..::|::...|||.:|...|:
  Rat   374 DYIW-----YSRHALSVTSALDLLTEEQ-IGPNRLPSFHYPSDHLSLVCDFS 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
angel	NP_477204.1	EEP	70..351	CDD:294334	85/300 (28%)
Noct	NP_612535.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..66
		Deadenylase_nocturnin	141..420	CDD:197330	86/304 (28%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q9UK39	216..218		1/1 (100%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q9UK39	283..286		2/2 (100%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:Q9UK39	321..323		1/1 (100%)
		Interaction with PPARG. /evidence=ECO:0000250\|UniProtKB:O35710	340..350		1/17 (6%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810