DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)efl and hspb8

DIOPT Version :9

Sequence 1:	NP_001261156.1	Gene:	l(2)efl / 37744	FlyBaseID:	FBgn0011296	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_001005658.1	Gene:	hspb8 / 448147	XenbaseID:	XB-GENE-945643	Length:	202	Species:	Xenopus tropicalis

Alignment Length:	159	Identity:	61/159 - (38%)
Similarity:	94/159 - (59%)	Gaps:	20/159 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PMR----TSRLLDQHFGQGLKRDDL-----------MSSVWNS--RPTVLRSGYLRP-WHTNSLQ 64
            |.|    :|||||:.||.....|||           ::|.|:.  |..::|||...| :::....
Frog    23 PFREQGLSSRLLDEDFGIPPFSDDLTMDWPDWARPRLTSAWSGPLRSGLVRSGMPPPVYNSRYTG 87

  Fly    65 KQESGSTLNIDSEKFEVILDVQQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLP 129
            ..::.:|:...|:.::|.::||.|.|.|:|||..|.||.|.|.|||:|.|.|.||:.|::::|||
Frog    88 YPDARNTVANISQPWKVCVNVQTFKPEELTVKTKDGFVEVSGNHEEQQKEGGIVSKNFTKKFQLP 152

  Fly   130 SDVNPDTVTSSLSSDGLLTIKAPMKALPP 158
            .:|:..||.:|||.:|||.|:||:  :||
Frog   153 PEVDAQTVFASLSPEGLLIIEAPV--VPP 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_001261156.1	metazoan_ACD	71..153	CDD:107247	39/81 (48%)
hspb8	NP_001005658.1	alpha-crystallin-Hsps_p23-like	86..175	CDD:381838	38/88 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920