DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)efl and Hsp67Ba

DIOPT Version :9

Sequence 1:	NP_001261156.1	Gene:	l(2)efl / 37744	FlyBaseID:	FBgn0011296	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_523998.1	Gene:	Hsp67Ba / 39076	FlyBaseID:	FBgn0001227	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	74/243 - (30%)
Similarity:	112/243 - (46%)	Gaps:	64/243 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVVPLMFRDWWDEL-DF-----------------PMRTSRLLDQHFGQGLKRDDLM-------- 39
            ||::|.:. |..:|| ||                 |:..:..|.| ..:||.|.:.|
  Fly     1 MSLIPFIL-DLAEELHDFNRSLAMDIDDSAGFGLYPLEATSQLPQ-LSRGLGRGNAMMWVPIKGQ 63

  Fly    40 --SSVWNSRPTVLRSGYLRPWHTNSLQKQE-----------SGSTLN-----------IDSEKFE 80
              :|.....|....:|........||.:.|           ||||..           ::...|:
  Fly    64 SAASQHRHHPYNRVAGAKTACCNKSLVELEKELGDKGTSGASGSTSGQPAASKSAYSVVNRNGFQ 128

  Fly    81 VILDVQQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSDVNPDTVTSSLSSDG 145
            |.::|:||:.:|:|||..|..::|||:|:||:|.||.:||.|.|:|.||...:|:.|.|:|||||
  Fly   129 VSMNVKQFAANELTVKTIDNCIVVEGQHDEKEDGHGVISRHFIRKYILPKGYDPNEVHSTLSSDG 193

  Fly   146 LLTIKAPMKALPP--------PQTERLVQITQTGPSSKEDNAKKVETS 185
            :||:|||    ||        .:.||:|.|.|.....|:.:|:..:.|
  Fly   194 ILTVKAP----PPLPVVKGSLERQERIVDIQQISQQQKDKDAQPPKPS 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_001261156.1	metazoan_ACD	71..153	CDD:107247	39/92 (42%)
Hsp67Ba	NP_523998.1	metazoan_ACD	124..200	CDD:107247	37/75 (49%)
Hsp67Ba	NP_523998.1	DNA_pol3_delta2	<218..>381	CDD:331068	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469594
Domainoid	1	1.000	51	1.000	Domainoid score	I4315
eggNOG	1	0.900	-	-		E1_KOG3591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I3937
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	1	1.000	-	-		FOG0000383
OrthoInspector	1	1.000	-	-		otm14686
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45640
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6558
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.930