DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)efl and Hspb2

DIOPT Version :9

Sequence 1:	NP_001261156.1	Gene:	l(2)efl / 37744	FlyBaseID:	FBgn0011296	Length:	187	Species:	Drosophila melanogaster
Sequence 2:	NP_569115.1	Gene:	Hspb2 / 161476	RGDID:	70914	Length:	182	Species:	Rattus norvegicus

Alignment Length:	167	Identity:	57/167 - (34%)
Similarity:	91/167 - (54%)	Gaps:	22/167 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SRLLDQHFGQGLKRDDLMSSVWNSRPTVLRSGYLRPWHTNSLQKQESG-STLNIDSEKFEVILDV 85
            |||.:|.||:||..:::::      ||:....|:||....:.:...:| |.|.:...||:..|||
  Rat    22 SRLGEQRFGEGLLPEEILT------PTLYHGYYVRPRAARAGEGGRAGASELRLSEGKFQAFLDV 80

  Fly    86 QQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSDVNPDTVTSSLSSDGLLTIK 150
            ..|:|.|:||:..|..:.|..:|.::.|.||:|||:|.|.|.||:||:|..|.::||.||:|.::
  Rat    81 SHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLE 145

  Fly   151 AP--------------MKALP-PPQTERLVQITQTGP 172
            ||              :..|| ||..|...::.:..|
  Rat   146 APRGGRHLDTEVNEVYISLLPAPPDPEEEEEVARVEP 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_001261156.1	metazoan_ACD	71..153	CDD:107247	36/95 (38%)
Hspb2	NP_569115.1	Crystallin	<16..51	CDD:395419	11/34 (32%)
Hspb2	NP_569115.1	alpha-crystallin-Hsps_p23-like	67..148	CDD:412199	35/80 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342768
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1187096at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750