Protein Alignment l(2)efl and CRYAB

DIOPT Version :10

• Sequence 1: NP_523827.1
• Gene: l(2)efl / 37744
• FlyBaseID: FBgn0011296
• Length: 187
• Species: Drosophila melanogaster
• Sequence 2: NP_001876.1
• Gene: CRYAB / 1410
• HGNCID: 2389
• Length: 175
• Species: Homo sapiens
• Alignment Length: 162
• Identity: 71/162 - (43%)
• Similarity: 97/162 - (59%)
• Gaps: 22/162 - (13%)

  Fly    17 FPMRT-SRLLDQHFGQGLKRDDLMSSVWNSRPTVLRSGYLRP--------WHTNSLQKQESGSTL 72
            ||..: |||.||.||:.|...||..:     .|.|...||||        |....|      |.:
Human    15 FPFHSPSRLFDQFFGEHLLESDLFPT-----STSLSPFYLRPPSFLRAPSWFDTGL------SEM 68

  Fly    73 NIDSEKFEVILDVQQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSDVNPDTV 137
            .::.::|.|.|||:.|||.|:.|||....:.|.|||||:|||||::||:|.|:|::|:||:|.|:
Human    69 RLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTI 133

  Fly   138 TSSLSSDGLLTIKAPMKALPPPQTERLVQITQ 169
            ||||||||:||:..|.|.:..|  ||.:.||:
Human   134 TSSLSSDGVLTVNGPRKQVSGP--ERTIPITR 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)efl	NP_523827.1	metazoan_ACD	71..153	CDD:107247	43/81 (53%)
CRYAB	NP_001876.1	Crystallin	1..55	CDD:425732	18/44 (41%)
		ACD_alphaB-crystallin_HspB5	67..150	CDD:107246	44/82 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..175		7/20 (35%)