DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(2)efl and Cryab

DIOPT Version :9

Sequence 1:NP_001261156.1 Gene:l(2)efl / 37744 FlyBaseID:FBgn0011296 Length:187 Species:Drosophila melanogaster
Sequence 2:NP_001276711.1 Gene:Cryab / 12955 MGIID:88516 Length:175 Species:Mus musculus


Alignment Length:162 Identity:72/162 - (44%)
Similarity:98/162 - (60%) Gaps:22/162 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 FPMRT-SRLLDQHFGQGLKRDDLMSSVWNSRPTVLRSGYLRP--------WHTNSLQKQESGSTL 72
            ||..: |||.||.||:.|...||.|:.     |.|...||||        |....|      |.:
Mouse    15 FPFHSPSRLFDQFFGEHLLESDLFSTA-----TSLSPFYLRPPSFLRAPSWIDTGL------SEM 68

  Fly    73 NIDSEKFEVILDVQQFSPSEITVKVADKFVIVEGKHEEKQDEHGYVSRQFSRRYQLPSDVNPDTV 137
            .::.::|.|.|||:.|||.|:.|||....:.|.|||||:|||||::||:|.|:|::|:||:|.|:
Mouse    69 RLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTI 133

  Fly   138 TSSLSSDGLLTIKAPMKALPPPQTERLVQITQ 169
            ||||||||:||:..|.|.:..|  ||.:.||:
Mouse   134 TSSLSSDGVLTVNGPRKQVSGP--ERTIPITR 163

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(2)eflNP_001261156.1 metazoan_ACD 71..153 CDD:107247 43/81 (53%)
CryabNP_001276711.1 Crystallin 1..52 CDD:395419 18/41 (44%)
ACD_alphaB-crystallin_HspB5 67..150 CDD:107246 44/82 (54%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 145..175 7/21 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167838979
Domainoid 1 1.000 105 1.000 Domainoid score I6647
eggNOG 1 0.900 - - E1_KOG3591
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H68209
Inparanoid 1 1.050 126 1.000 Inparanoid score I4671
Isobase 1 0.950 - 0 Normalized mean entropy S4216
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1187096at2759
OrthoFinder 1 1.000 - - FOG0000383
OrthoInspector 1 1.000 - - otm43786
orthoMCL 1 0.900 - - OOG6_101545
Panther 1 1.100 - - O PTHR45640
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6558
SonicParanoid 1 1.000 - - X393
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
1514.780

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